Adult living-related liver donation for acute liver failure: is it ethically appropriate?

Erica M CARLISLE; Peter ANGELOS; Mark SIEGLER; Giuliano TESTA

doi:10.1111/j.1399-0012.2011.01413.x

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Adult living-related liver donation for acute liver failure: is it ethically appropriate?

Journal article

Peer reviewed

Adult living-related liver donation for acute liver failure: is it ethically appropriate?

Erica M CARLISLE, Peter ANGELOS, Mark SIEGLER and Giuliano TESTA

Clinical transplantation, Vol.25(6), pp.813-820

2011

DOI: 10.1111/j.1399-0012.2011.01413.x

PMID: 21320164

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Abstract

Acute liver failure (ALF) results in the annual death of approximately 3.5 per million people in the United States. Unfortunately, given the marked shortage of cadaveric liver donations and the ethical questions that plague utilization of living donor liver transplantation (LDLT) for ALF, many patients with ALF die before a liver is allocated to them. In this review, we discuss how the consistent utilization of LDLT for ALF could decrease the mortality rate of ALF. Additionally, we examine a key underlying issue: is LDLT for ALF ethically appropriate?

Fundamental and applied biological sciences. Psychology

Gastroenterology. Liver. Pancreas. Abdomen

Fundamental immunology

Tissue, organ and graft immunology

Liver. Biliary tract. Portal circulation. Exocrine pancreas

Liver, biliary tract, pancreas, portal circulation, spleen

Biological and medical sciences

Medical sciences

Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases

Surgery of the digestive system

Other diseases. Semiology

Details

Title: Subtitle: Adult living-related liver donation for acute liver failure: is it ethically appropriate?
Creators: Erica M CARLISLE - Department of Surgery, University of Chicago Medical Center, United States
Peter ANGELOS - Department of Surgery, University of Chicago Medical Center, United States
Mark SIEGLER - MacLean Center for Clinical Medical Ethics, University of Chicago Medical Center, Chicago, IL, United States
Giuliano TESTA - Department of Surgery, University of Chicago Medical Center, United States
Resource Type: Journal article
Publication Details: Clinical transplantation, Vol.25(6), pp.813-820
Publisher: Wiley; Hoboken, NJ
DOI: 10.1111/j.1399-0012.2011.01413.x
PMID: 21320164
ISSN: 0902-0063
eISSN: 1399-0012
Language: English
Date published: 2011
Academic Unit: Stead Family Department of Pediatrics; Surgery
Record Identifier: 9984051730502771

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