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Adult to adult living related liver transplantation: where do we currently stand?
Journal article   Open access   Peer reviewed

Adult to adult living related liver transplantation: where do we currently stand?

Erica M Carlisle and Giuliano Testa
World journal of gastroenterology : WJG, Vol.18(46), pp.6729-6736
12/14/2012
DOI: 10.3748/wjg.v18.i46.6729
PMCID: PMC3520161
PMID: 23239910
url
https://doi.org/10.3748/wjg.v18.i46.6729View
Published (Version of record) Open Access

Abstract

Adult to adult living donor liver transplantation (AALDLT) was first preformed in the United States in 1997. The procedure was rapidly integrated into clinical practice, but in 2002, possibly due to the first widely publicized donor death, the number of living liver donors plummeted. The number of donors has since reached a steady plateau far below its initial peak. In this review we evaluate the current climate of AALDLT. Specifically, we focus on several issues key to the success of AALDLT: determining the optimal indications for AALDLT, balancing graft size and donor safety, assuring adequate outflow, minimizing biliary complications, and maintaining ethical practices. We conclude by offering suggestions for the future of AALDLT in United States transplantation centers.
Ethics, Medical United States Humans Organ Size Treatment Outcome Liver Transplantation - trends Living Donors Liver Transplantation - methods Tissue and Organ Procurement - trends Liver Failure - therapy Tissue and Organ Procurement - methods Patient Safety Adult

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