Journal article
Advancements in nanosensors using plastic antibodies
Analyst (London), Vol.139(1), pp.21-31
01/07/2014
DOI: 10.1039/C3AN01725G
PMID: 24179993
Abstract
Biosensors possess recognition elements that bind to target molecules which lead to detectable signals. Incorporation of noble metal nanomaterials into biosensors allows for rapid and simple biomolecule detection. Herein, recent developments in affinity nanosensors will be discussed. These sensors often include naturally occurring recognition elements such as antibodies and DNA. As samples become more complex, new recognition elements are sought. For instance, plastic antibodies provide alternative and more environmentally stable recognition elements than traditional antibodies. Molecular imprinted polymers, a class of plastic antibodies, promote biomolecule recognition and detection. The incorporation of noble metal nanomaterials into molecular imprinted polymer biosensors for real world applications will be explored. Further improvements in the design of artificial recognition agents are envisioned to facilitate new methods for complex biological and chemical analyses.
Details
- Title: Subtitle
- Advancements in nanosensors using plastic antibodies
- Creators
- Anna A Volkert - University of Iowa, Department of Chemistry, 204 IATL, Iowa City, Iowa 52242, USA. amanda-haes@uiowa.eduAmanda J Haes
- Resource Type
- Journal article
- Publication Details
- Analyst (London), Vol.139(1), pp.21-31
- Publisher
- England
- DOI
- 10.1039/C3AN01725G
- PMID
- 24179993
- ISSN
- 0003-2654
- eISSN
- 1364-5528
- Language
- English
- Date published
- 01/07/2014
- Academic Unit
- Chemistry
- Record Identifier
- 9983985857402771
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