Aging is not accompanied by sympathetic hyperresponsiveness to air-jet stress

Harald M Stauss; Donald A Morgan; Karl E Anderson; Michael P Massett; Kevin C Kregel

doi:10.1152/ajpheart.1996.271.2.h768

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Aging is not accompanied by sympathetic hyperresponsiveness to air-jet stress

Journal article

Peer reviewed

Aging is not accompanied by sympathetic hyperresponsiveness to air-jet stress

Harald M Stauss, Donald A Morgan, Karl E Anderson, Michael P Massett and Kevin C Kregel

The American journal of physiology, Vol.271(2 Pt 2), pp.H768-H775

08/1996

DOI: 10.1152/ajpheart.1996.271.2.h768

PMID: 8770121

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Abstract

It has been postulated that sympathetic nervous system reactivity to acutely applied stress is increased with age. We investigated the autonomic and hemodynamic adjustments to air-jet stress in 9 mature (12-mo-old) and 11 senescent (24-mo-old) Fischer 344 rats. Rats were instrumented with arterial and venous catheters, flow probes around the renal artery, and nerve electrodes on the ipsilateral renal nerve. After the rats recovered from surgery, blood pressure, heart rate, renal blood flow, and renal sympathetic nerve activity were recorded during control conditions and during an 8-min continuous air-jet application. Renal resistance and the low (0.01-0.20 Hz)- and mid-frequency (0.20-0.50 Hz) power of blood pressure were computed off-line. The air jet induced an increase in blood pressure, heart rate, renal resistance, renal nerve activity, and blood pressure power in the low- and mid-frequency ranges in both groups. Blood pressure and low-frequency blood pressure power increased less, and the elevations in renal resistance and renal nerve activity were of shorter duration in senescent compared with mature rats. These data suggest that sympathetic responsiveness to air-jet stress is not enhanced with increasing age.

Aging - physiology

Air

Animals

Blood Pressure

Cardiovascular System - physiopathology

Heart Rate

Kidney - innervation

Physical Stimulation

Rats

Rats, Inbred F344

Renal Circulation - physiology

Stress, Physiological - physiopathology

Sympathetic Nervous System - physiopathology

Details

Title: Subtitle: Aging is not accompanied by sympathetic hyperresponsiveness to air-jet stress
Creators: Harald M Stauss - Department of Exercise Science, University of Iowa, Iowa City 52242, USA
Donald A Morgan
Karl E Anderson
Michael P Massett
Kevin C Kregel
Resource Type: Journal article
Publication Details: The American journal of physiology, Vol.271(2 Pt 2), pp.H768-H775
DOI: 10.1152/ajpheart.1996.271.2.h768
PMID: 8770121
NLM abbreviation: Am J Physiol
ISSN: 0002-9513
eISSN: 2163-5773
Grant note: AG-12350 / NIA NIH HHS
Language: English
Date published: 08/1996
Academic Unit: Radiation Oncology; Neuroscience and Pharmacology; Provost Office Administration; Health, Sport, and Human Physiology
Record Identifier: 9984213452002771

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