Agouti-related protein neuron circuits that regulate appetite

Scott M Sternson; Deniz Atasoy

doi:10.1159/000369072

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Agouti-related protein neuron circuits that regulate appetite

Journal article

Open access

Peer reviewed

Agouti-related protein neuron circuits that regulate appetite

Scott M Sternson and Deniz Atasoy

Neuroendocrinology, Vol.100(2-3), pp.95-102

2014

DOI: 10.1159/000369072

PMID: 25402352

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https://doi.org/10.1159/000369072View

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Abstract

New tools for mapping and manipulating molecularly defined neural circuits have improved the understanding of how the central nervous system regulates appetite. Studies that focused on Agouti-related protein neurons, a starvation-sensitive hypothalamic population, have identified multiple circuit elements that can elicit or suppress feeding behavior. Distinct axon projections of this neuron population point to different circuits that regulate long-term appetite, short-term feeding, or visceral malaise-mediated anorexia. Here, we review recent studies examining these neural circuits that control food intake.

Animals

Appetitive Behavior - physiology

Brain - physiopathology

Neurons - physiology

Appetite Regulation - physiology

Agouti-Related Protein - metabolism

Brain - physiology

Neural Pathways - physiology

Anorexia - physiopathology

Details

Title: Subtitle: Agouti-related protein neuron circuits that regulate appetite
Creators: Scott M Sternson - Janelia Research Campus, HHMI, Ashburn, Va., USA
Deniz Atasoy
Resource Type: Journal article
Publication Details: Neuroendocrinology, Vol.100(2-3), pp.95-102
Publisher: Switzerland
DOI: 10.1159/000369072
PMID: 25402352
ISSN: 0028-3835
eISSN: 1423-0194
Language: English
Date published: 2014
Academic Unit: Iowa Neuroscience Institute; Fraternal Order of Eagles Diabetes Research Center; Neuroscience and Pharmacology
Record Identifier: 9984040263902771

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