Journal article
Agreement Between Fixed-Ratio and Lower Limit of Normal Spirometry Interpretation Protocols Decreases With Age: Is There a Need for a New GOLD Standard?
Journal of occupational and environmental medicine, Vol.55(7), pp.802-808
2013
DOI: 10.1097/JOM.0b013e31828b22cc
PMID: 23787569
Abstract
Objectives: To assess concordance between the fixed 70% ratio cutoff point with the fixed percent predicted values (Fixed-ratio) and the lower limit of normal (LLN) algorithms in interpreting spirometry results in an older population.
Methods: Spirometries were interpreted using Third National Health and Nutrition Examination Survey reference equations for 2319 workers.
Results: The Fixed-ratio algorithm characterized 34.5% (n = 801) results as abnormal, compared with 29.7% (n = 689) by the LLN. There were almost twice as many obstructive and mixed airways spirometries identified under the Fixed-ratio compared to LLN. Rates of restrictive pattern physiology were virtually the same under each algorithm. Overall agreement between the algorithms decreased with age from "almost perfect" for those younger than 60 years to "substantial" for those older than 80 years.
Conclusions: This study found age-related discordance between two algorithms possibly related to the lack of reference equations and standards for individuals older than 80 years.
Details
- Title: Subtitle
- Agreement Between Fixed-Ratio and Lower Limit of Normal Spirometry Interpretation Protocols Decreases With Age: Is There a Need for a New GOLD Standard?
- Creators
- Marek A Mikulski - Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, Iowa City, United StatesAlicia K Gerke - Department of Internal Medicine, The University of Iowa, Iowa City, United StatesSpencer Lourens - Department of Biostatistics, College of Public Health, The University of Iowa, Iowa City, United StatesThomas Czeczok - Roy J. and Lucille Carver College of Medicine, The University of Iowa, Iowa City, United StatesNancy L Sprince - Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, Iowa City, United StatesAnthony S Laney - Surveillance Branch , Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WVa, United StatesLaurence J Fuortes - Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, Iowa City, United States
- Resource Type
- Journal article
- Publication Details
- Journal of occupational and environmental medicine, Vol.55(7), pp.802-808
- Publisher
- Lippincott Williams & Wilkins
- DOI
- 10.1097/JOM.0b013e31828b22cc
- PMID
- 23787569
- ISSN
- 1076-2752
- eISSN
- 1536-5948
- Language
- English
- Date published
- 2013
- Academic Unit
- Pulmonary, Critical Care, and Occupational Medicine; Occupational and Environmental Health; Internal Medicine
- Record Identifier
- 9984094720402771
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