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Alagille Syndrome and Chronic Arthritis: An International Case Series
Journal article   Peer reviewed

Alagille Syndrome and Chronic Arthritis: An International Case Series

Giovanna Ferrara, Teresa Giani, Scott M. Lieberman, Courtney Kremer, Sandy Hong, Giuseppe Indolfi, Grant Schulert, Randy Q. Cron, Melissa L. Mannion, Sivia Lapidus, …
The Journal of pediatrics, Vol.218, pp.228-230.e1
03/01/2020
DOI: 10.1016/j.jpeds.2019.10.042
PMID: 31748120

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Abstract

We describe 10 children with Alagille syndrome and inflammatory arthritis. In our centers, the prevalence of chronic arthritis in patients with Alagille syndrome is approximately 50 times higher compared with the general population. Arthritis was refractory to most treatment. Patients with Alagille syndrome should routinely be screened for musculoskeletal symptoms.
Pediatrics Life Sciences & Biomedicine Science & Technology

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