Journal article
Alcohol Disorders: Practical Tips From New Research
The Psychiatric times, Vol.29(9), p.19
09/01/2012
Abstract
According to the World Health Organization, AUDs have the highest morbidity and mortality burden worldwide (2.5 million deaths every year) and are associated with wide-reaching social problems. A recent Cochrane review reported that anticonvulsants may be more effective than benzodiazepines in treating some aspects of alcohol withdrawal syndrome (ie, decreasing seizure risk).9 Findings from a retrospective cohort study of 453 patients treated with valproate and 374 patients treated with carbamazepine suggest that valproate may have more benefits because of its higher tolerability, shorter duration of treatment, and lower incidence of alcohol-withdrawal seizures.10 The anticonvulsants gabapentin and pregabalin are used primarily for neuropathic pain and partial seizure prophylaxis. Because of their effects on GABAergic neurotransmission, they are also rational medications for alcohol withdrawal syndrome.
Details
- Title: Subtitle
- Alcohol Disorders: Practical Tips From New Research
- Creators
- Mark J Niciu JrIsmene Petrakis
- Resource Type
- Journal article
- Publication Details
- The Psychiatric times, Vol.29(9), p.19
- Publisher
- UBM LLC; Monmouth Junction
- ISSN
- 0893-2905
- Language
- English
- Date published
- 09/01/2012
- Academic Unit
- Psychiatry; Iowa Neuroscience Institute
- Record Identifier
- 9984071613402771
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