Alcohol consumption, hypertension, and total mortality among women

Matthew S Freiberg; Yue-Fang Chang; Kevin L Kraemer; Jennifer G Robinson; Lucile L Adams-Campbell; Lewis L Kuller

doi:10.1038/ajh.2009.172

Back

Alcohol consumption, hypertension, and total mortality among women

Journal article

Open access

Peer reviewed

Alcohol consumption, hypertension, and total mortality among women

Matthew S Freiberg, Yue-Fang Chang, Kevin L Kraemer, Jennifer G Robinson, Lucile L Adams-Campbell and Lewis L Kuller

American journal of hypertension, Vol.22(11), pp.1212-1218

11/2009

DOI: 10.1038/ajh.2009.172

PMCID: PMC3104852

PMID: 19730413

Files and links (1)

url

https://doi.org/10.1038/ajh.2009.172View

Published (Version of record) Open Access

Abstract

Moderate alcohol consumption is associated with a reduced risk of total mortality among Caucasian women. Whether moderate alcohol consumption is associated with a reduced risk of total mortality among African-American or hypertensive women is unclear. We conducted a prospective study among 10,576 black and 105,610 white postmenopausal women from the Women's Health Initiative (WHI), without a history of cancer or cardiovascular disease, who completed the baseline examinations in 1994-1998. During the mean 8 years of follow-up, 5,608 women died. Moderate drinking (1 to <7 drinks/week) was associated with a lower risk of total mortality among Caucasians (hazard ratio (HR) = 0.81, 95% confidence interval (CI) = 0.72-0.91) and hypertensives (HR = 0.76, 95% CI = 0.65-0.87) as compared with lifetime abstention from alcohol. Among African-American moderate drinkers the risk of total mortality was HR = 0.94, 95% CI = 0.67-1.3. Current drinking (<1 drink/month or greater) was associated with a lower risk of mortality among Caucasians, including hypertensives and nonhypertensives, and hypertensive African Americans (HR = 0.74, 95% CI = 0.54-0.99) but not among nonhypertensive African Americans (HR = 1.31, 95% CI = 0.79-2.16). The stratified comparisons among African Americans were affected by the low prevalence of moderate drinking (14.6%) and the low mortality rate (37.5/10,000) among the nonhypertensive lifetime abstainers. Moderate drinking is associated with a lower risk of total mortality among Caucasian women. Current drinking is associated with a lower risk of total mortality among Caucasians, regardless of hypertensive status, and hypertensive but not nonhypertensive African-American women. The latter observation was affected by the low mortality rate among the African-American nonhypertensive lifetime abstainers.

Demography

United States

Humans

Middle Aged

Risk Factors

Postmenopause - ethnology

European Continental Ancestry Group - ethnology

African Americans - ethnology

Hypertension - ethnology

Female

Aged

Hypertension - mortality

Alcohol Drinking - ethnology

Alcohol Drinking - mortality

Details

Title: Subtitle: Alcohol consumption, hypertension, and total mortality among women
Creators: Matthew S Freiberg - University of Pittsburgh, Pittsburgh, Pennsylvania, USA. freibergms@upmc.edu
Yue-Fang Chang
Kevin L Kraemer
Jennifer G Robinson
Lucile L Adams-Campbell
Lewis L Kuller
Resource Type: Journal article
Publication Details: American journal of hypertension, Vol.22(11), pp.1212-1218
Publisher: United States
DOI: 10.1038/ajh.2009.172
PMID: 19730413
PMCID: PMC3104852
ISSN: 0895-7061
eISSN: 1879-1905
Grant note: K23 AA015914-04 / NIAAA NIH HHS K23 AA015914 / NIAAA NIH HHS
Language: English
Date published: 11/2009
Academic Unit: Epidemiology; Internal Medicine
Record Identifier: 9983995151402771

Metrics

23 Record Views

19 Times Cited - Web of Science