Journal article
Alkylation reactions of phosphachroman-2,4-diones and 4-hydroxy phosphacoumarins
Bioorganic chemistry, Vol.34(2), pp.105-113
2006
DOI: 10.1016/j.bioorg.2006.01.003
PMID: 16524614
Abstract
Phosphachroman-2,4-dione and 4-alkoxyphosphacoumarin derivatives, phosphonic analogues of chromones and coumarins with potential biological activities, were synthesized in good yields through sequential base-catalyzed intramolecular cyclization of
O-alkyl-
O′-(2′-methoxycarbonyl phenyl)-(substituted) benzyl phosphonates and alkylation. The synthesis sets the stage for an examination of the biological activities.
Details
- Title: Subtitle
- Alkylation reactions of phosphachroman-2,4-diones and 4-hydroxy phosphacoumarins
- Creators
- Xueshu Li - Tsinghua UniversityYitong Wang - Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, PR ChinaHua Fu - Tsinghua UniversityYuyang Jiang - Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, PR ChinaYufen Zhao - Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, PR China
- Resource Type
- Journal article
- Publication Details
- Bioorganic chemistry, Vol.34(2), pp.105-113
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.bioorg.2006.01.003
- PMID
- 16524614
- ISSN
- 0045-2068
- eISSN
- 1090-2120
- Language
- English
- Date published
- 2006
- Academic Unit
- Occupational and Environmental Health
- Record Identifier
- 9984303459902771
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