Journal article
Allelic Interactions at the Shibire Locus of Drosophila: Effects on Behavior
Journal of neurogenetics, Vol.7(1), pp.1-14
1990
DOI: 10.3109/01677069009084149
PMID: 2099381
Abstract
This report describes a detailed behavioral study of four shi alleles, shits1, shits2, shits4, and shiST139, and their heteroallelic combinations. Flies of different heteroallelic combinations (shi/shi) were less sensitive to high temperature than the corresponding homozygotes. Among them, shits2/shits4 showed a striking reduction in temperature sensitivity. In contrast, different shi/+ heterozygotes were more severe in temperature sensitivity than the hemizygotes, Df/+. The hemizygous combinations of shi alleles over deficiency (shi/Df) were not completely lethal, with shits2 conferring distinctively higher and shits4 lower viability. A novel behavior, bang sensitivity, was also found in shi/Df. The results of allelic interactions suggest that the shi mutations examined appear to be antimorphic and that the shi gene products are likely to function in multimeric form.
Details
- Title: Subtitle
- Allelic Interactions at the Shibire Locus of Drosophila: Effects on Behavior
- Creators
- Yun-Taik Kim - 1Department of Biology, The University of Iowa, Iowa City, IA 52242Chun-Fang Wu - 1Department of Biology, The University of Iowa, Iowa City, IA 52242
- Resource Type
- Journal article
- Publication Details
- Journal of neurogenetics, Vol.7(1), pp.1-14
- Publisher
- Informa UK Ltd
- DOI
- 10.3109/01677069009084149
- PMID
- 2099381
- ISSN
- 0167-7063
- eISSN
- 1563-5260
- Language
- English
- Date published
- 1990
- Academic Unit
- Iowa Neuroscience Institute; Biology
- Record Identifier
- 9984070488802771
Metrics
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