Allergenic components of vaccines and avoidance of vaccination-related adverse events

J W Georgitis; M B Fasano

doi:10.1007/s11882-001-0091-6

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Journal article

Allergenic components of vaccines and avoidance of vaccination-related adverse events

J W Georgitis and M B Fasano

Current allergy reports, Vol.1(1), p.11

01/2001

DOI: 10.1007/s11882-001-0091-6

PMID: 11899279

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Abstract

Vaccines have had a dramatic effect on the prevalence of communicable diseases, but, in selected individuals, the injection presents a risk of anaphylaxis. Fortunately, most people have no allergic reactions to vaccines. In egg-allergic individuals, care must be taken before administering specific vaccines; the algorithm provided in this article gives specific recommendations for skin testing and desensitization. This algorithm is not needed for individuals receiving the measles-mumps-rubella vaccine because the risk of anaphylaxis is extremely low, even in those with known egg-protein sensitivity. Some individuals have gelatin sensitivity, which may cause anaphylaxis. Selected vaccines contain antibiotic drugs, so it is important to note if an individual has any known drug sensitivity, especially to neomycin, polymyxin B, or amphotericin B. Lastly, vaccine preservatives may cause reactions, but this occurs very infrequently.

Drug Hypersensitivity - etiology

Allergens - adverse effects

United States - epidemiology

Vaccines - adverse effects

Allergens - therapeutic use

Allergens - immunology

Hypersensitivity - etiology

Humans

Antibodies - immunology

Vaccines - immunology

Antibodies - adverse effects

Vaccination - adverse effects

Details

Title: Subtitle: Allergenic components of vaccines and avoidance of vaccination-related adverse events
Creators: J W Georgitis - Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA. jgeorgit@wfubmc.edu
M B Fasano
Resource Type: Journal article
Publication Details: Current allergy reports, Vol.1(1), p.11
DOI: 10.1007/s11882-001-0091-6
PMID: 11899279
NLM abbreviation: Curr Allergy Asthma Rep
ISSN: 1529-7322
eISSN: 1534-6315
Language: English
Date published: 01/2001
Academic Unit: Stead Family Department of Pediatrics; Rheumatology, Allergy, and Immunology; Immunology; Internal Medicine
Record Identifier: 9984093489102771

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