Journal article
Altenuene Derivatives from an Unidentified Freshwater Fungus in the Family Tubeufiaceae
Journal of natural products (Washington, D.C.), Vol.69(4), pp.612-615
04/2006
DOI: 10.1021/np0504661
PMCID: PMC2527179
PMID: 16643037
Abstract
Four new altenuene derivatives called dihydroaltenuenes A (
1
) and B (
2
), and dehydroaltenuenes A (
3
) and B (
4
), along with five known compounds, including isoaltenuene (
5
), altenuene (
6
) and 5′-epialtenuene (
7
), were isolated from cultures of an unidentified freshwater aquatic fungal species in the family Tubeufiaceae. The structures of
1
–
4
were determined by analysis of NMR and MS data. The relative stereochemistry was determined on the basis of
1
H NMR
J
-values and NOE data, while the absolute configuration of a representative member of the group (
5
) was assigned by CD spectral analysis of its
bis
-N,Ndimethylaminobenzoate derivative. Compounds
1
,
3, 4, 5
, and
6
showed antibiotic activity against Gram-positive bacteria.
Details
- Title: Subtitle
- Altenuene Derivatives from an Unidentified Freshwater Fungus in the Family Tubeufiaceae
- Creators
- Ping Jiao - Department of Chemistry, University of Iowa, Iowa City, IA, 52246 Department of Plant Biology, University of Illinois, Urbana, IL, 61801James B Gloer - Department of Chemistry, University of Iowa, Iowa City, IA, 52246 Department of Plant Biology, University of Illinois, Urbana, IL, 61801Jinx Campbell - Department of Chemistry, University of Iowa, Iowa City, IA, 52246 Department of Plant Biology, University of Illinois, Urbana, IL, 61801Carol A Shearer - Department of Chemistry, University of Iowa, Iowa City, IA, 52246 Department of Plant Biology, University of Illinois, Urbana, IL, 61801
- Resource Type
- Journal article
- Publication Details
- Journal of natural products (Washington, D.C.), Vol.69(4), pp.612-615
- DOI
- 10.1021/np0504661
- PMID
- 16643037
- PMCID
- PMC2527179
- NLM abbreviation
- J Nat Prod
- ISSN
- 0163-3864
- eISSN
- 1520-6025
- Language
- English
- Date published
- 04/2006
- Academic Unit
- Chemistry
- Record Identifier
- 9984216564302771
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