Altered brain structures in the dorsal and ventral language pathways in individuals with and without developmental language disorder (DLD)

Joanna C Lee; Anthony Steven Dick; J Bruce Tomblin

doi:10.1007/s11682-019-00209-1

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Altered brain structures in the dorsal and ventral language pathways in individuals with and without developmental language disorder (DLD)

Journal article

Peer reviewed

Altered brain structures in the dorsal and ventral language pathways in individuals with and without developmental language disorder (DLD)

Joanna C Lee, Anthony Steven Dick and J Bruce Tomblin

Brain imaging and behavior, Vol.14(6), pp.2569-2586

12/2020

DOI: 10.1007/s11682-019-00209-1

PMCID: PMC7354888

PMID: 31933046

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https://www.ncbi.nlm.nih.gov/pmc/articles/7354888View

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Abstract

Developmental Language Disorder (DLD) is a neurodevelopmental disorder characterized by difficulty learning and using language, and this difficulty cannot be attributed to other developmental conditions. The aim of the current study was to examine structural differences in dorsal and ventral language pathways between adolescents and young adults with and without DLD (age range: 14-27 years) using anatomical magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI). Results showed age-related structural brain differences in both dorsal and ventral pathways in individuals with DLD. These findings provide evidence for neuroanatomical correlates of persistent language deficits in adolescents/young adults with DLD, and further suggest that this brain-language relationship in DLD is better characterized by taking account the dynamic course of the disorder along development.

Young Adult

Magnetic Resonance Imaging

Brain - diagnostic imaging

Language

Humans

Adolescent

Language Development Disorders - diagnostic imaging

Adult

Female

Male

Diffusion Tensor Imaging

Details

Title: Subtitle: Altered brain structures in the dorsal and ventral language pathways in individuals with and without developmental language disorder (DLD)
Creators: Joanna C Lee - Department of Communication Sciences and Disorders, University of Iowa, Iowa City, IA, 52242, USA. joannachen-lee@uiowa.edu
Anthony Steven Dick - Department of Psychology, Florida International University, Miami, FL, USA
J Bruce Tomblin - Department of Communication Sciences and Disorders, University of Iowa, Iowa City, IA, 52242, USA
Resource Type: Journal article
Publication Details: Brain imaging and behavior, Vol.14(6), pp.2569-2586
DOI: 10.1007/s11682-019-00209-1
PMID: 31933046
PMCID: PMC7354888
NLM abbreviation: Brain Imaging Behav
ISSN: 1931-7557
eISSN: 1931-7565
Publisher: United States
Grant note: R21 DC013733 / NIDCD NIH HHS R21DC013733 / NIDCD NIH HHS
Language: English
Date published: 12/2020
Academic Unit: Communication Sciences and Disorders; Iowa Neuroscience Institute
Record Identifier: 9984070823602771

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