Journal article
Alternative grafts in anterior cervical fusion
Clinical neurology and neurosurgery, Vol.115(10), pp.2049-2055
10/2013
DOI: 10.1016/j.clineuro.2013.07.013
PMID: 23911002
Abstract
The present retrospective study was conducted to compare the clinical and radiographic outcomes in patients undergoing anterior cervical discectomy with fusion (ACDF) using carbon fiber reinforced polymer (CFRP) cages, or allograft.
We retrospectively reviewed cases of ACDF using allograft in 20 patients, and CFRP in 19 who had sequential radiographs before and after surgery, and at 1 year.
There were no apparent significant differences between the 2 groups in age (p=0.057), gender (p=0.635), or complications (p=0.648). At 12 months, there were no cases of construct failure, and fusion appeared to have been achieved in patients of both groups. Lordosis was increased significantly in both groups after surgery (p<0.001 in allograft and p=0.025 in CFRP), and was maintained up until 1 year (p<0.018 in allograft and p=0.05 in CFRP) without a difference between groups (p=0.721). Anterior interbody height was significantly increased (p<0.001 in both groups at each time points) after surgery, without a significant difference between groups (p>0.21). This increase in height was greatest in magnitude immediately after surgery, and declined with the passage of time. There was no detectable health-related quality of life difference between allograft and CFRP group after surgery (p>0.05).
The present study demonstrates that CFRP cages appear to have comparable fusion rates, restoration of lordosis and disc space height, and complication rates to patients who undergo ACDF with allograft.
Details
- Title: Subtitle
- Alternative grafts in anterior cervical fusion
- Creators
- Fangxiang Chen - Department of Neurological Surgery, University of Iowa Hospitals and Clinics (UIHC), 200 Hawkins Drive, Iowa City, USAWenzhuan He - Department of Neurological Surgery, University of Iowa Hospitals and Clinics (UIHC), 200 Hawkins Drive, Iowa City, USAKelly Mahaney - Department of Neurological Surgery, University of Iowa Hospitals and Clinics (UIHC), 200 Hawkins Drive, Iowa City, USAJennifer Noeller - Department of Neurological Surgery, University of Iowa Hospitals and Clinics (UIHC), 200 Hawkins Drive, Iowa City, USANakhle Mhanna - Department of Neurological Surgery, University of Iowa Hospitals and Clinics (UIHC), 200 Hawkins Drive, Iowa City, USAStephen Viljoen - Department of Neurological Surgery, University of Iowa Hospitals and Clinics (UIHC), 200 Hawkins Drive, Iowa City, USAJames Torner - Department of Epidemiology and Statistics, University of Iowa Hospitals and Clinics (UIHC), 200 Hawkins Drive, Iowa City, USAPatrick Hitchon - Department of Neurological Surgery, University of Iowa Hospitals and Clinics (UIHC), 200 Hawkins Drive, Iowa City, USA
- Resource Type
- Journal article
- Publication Details
- Clinical neurology and neurosurgery, Vol.115(10), pp.2049-2055
- DOI
- 10.1016/j.clineuro.2013.07.013
- PMID
- 23911002
- NLM abbreviation
- Clin Neurol Neurosurg
- ISSN
- 0303-8467
- eISSN
- 1872-6968
- Publisher
- Elsevier B.V
- Language
- English
- Date published
- 10/2013
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Epidemiology; Surgery; Injury Prevention Research Center; Neurosurgery
- Record Identifier
- 9983995053902771
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