Journal article
Alzheimer’s Model Develops Early ADHD Syndrome
Journal of neurology & neurophysiology, Vol.6(6), pp.1-6
2015
PMCID: PMC4704098
PMID: 26753104
Abstract
We describe the first invertebrate model of attention deficit hyperactivity disorder (ADHD) that reproduces its major features, including hyperactivity, male predominance, marked exacerbation by simple carbohydrates, reversible response to dextroamphetamine, and a “paradoxical response” to stimulants. This model may offer new insight into ADHD pathogenesis and treatment. Furthermore, these findings are of particular interest in light of the recent epidemiological evidence showing that patients with dementia have a high frequency of antecedent ADHD symptoms.
Details
- Title: Subtitle
- Alzheimer’s Model Develops Early ADHD Syndrome
- Creators
- Qiang Zhang - Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA 94945, USAGuiping Du - Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA 94945, USAV John - Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA 94945, USAPankaj Kapahi - Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA 94945, USADale E Bredesen - Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA 94945, USA
- Resource Type
- Journal article
- Publication Details
- Journal of neurology & neurophysiology, Vol.6(6), pp.1-6
- PMID
- 26753104
- PMCID
- PMC4704098
- ISSN
- 2155-9562
- eISSN
- 2155-9562
- Language
- English
- Date published
- 2015
- Academic Unit
- Neurology
- Record Identifier
- 9984020739902771
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