Journal article
Ambient Air Pollution Exposure and Sleep Quality in COPD
Chronic obstructive pulmonary diseases, Vol.10(1), pp.102-111
01/04/2023
DOI: 10.15326/jcopdf.2022.0350
PMCID: PMC9995229
PMID: 36599095
Abstract
Ambient air pollution exposure is associated with respiratory morbidity among individuals with chronic obstructive pulmonary disease (COPD), particularly among those with concomitant obesity. Although people with COPD report high incidence of poor sleep quality, no studies have evaluated the association between air pollution exposure, obesity, and sleep disturbances in COPD.
We analyzed data collected from current and former smokers with COPD enrolled in the Subpopulations and Intermediate Outcome Measures in COPD pollution ancillary study (SPIROMICS-AIR). Socio-demographics and anthropometric measurements were collected, and 1-year mean historical ambient particulate matter (PM
) and ozone concentrations at participants' residences were estimated by cohort-specific spatiotemporal modeling. Sleep quality was assessed with the Pittsburgh sleep quality index (PSQI), and regression models were constructed to determine the association of 1Yr-PM
and 1Yr-ozone with PSQI score, and whether obesity modified the association.
In 1,308 participants (age: 65.8±7.8 years, 42% women), results of regression analyses suggest that each 10 µg/m
increase in 1Yr-PM
was associated with a 2.1-point increase in PSQI (
=0.03). Obesity modified the association between 1Yr-PM
and PSQI (
=0.03). In obese and overweight participants, 10 µg/m
increase in 1Yr-PM
was associated with higher PSQI (4.0 points,
<0.01, and 3.4 points,
<0.01, respectively); but no association in lean-normal weight participants (
=0.51). There was no association between 1 Yr-ozone and PSQI.
Overweight and obese individuals with COPD, appear to be susceptible to the effects of ambient PM
on sleep quality. In COPD, weight and ambient PM
may be modifiable risk factors to improve sleep quality.
Details
- Title: Subtitle
- Ambient Air Pollution Exposure and Sleep Quality in COPD
- Creators
- Mudiaga O Sowho - Johns Hopkins UniversityAbigail L Koch - University of MiamiNirupama Putcha - Johns Hopkins UniversityHan Woo - Johns Hopkins UniversityAmanda Gassett - University of WashingtonLaura M Paulin - Dartmouth–Hitchcock Medical CenterKirsten Koehler - Johns Hopkins UniversityR Graham Barr - Columbia University Irving Medical CenterAlejandro P Comellas - University of IowaChristopher B Cooper - University of California, Los AngelesIgor Barjaktarevic - University of California, Los AngelesMichelle R Zeidler - University of California, Los AngelesMartha E Billings - University of WashingtonRussell P Bowler - National Jewish HealthMeiLan K Han - University of Michigan–Ann ArborVictor Kim - Temple UniversityRobert Paine III - University of UtahTrisha M Parekh - University of Alabama at BirminghamJerry A Krishnan - University of Illinois at ChicagoStephen P Peters - Wake Forest UniversityPrescott G Woodruff - University of California, San FranciscoAaron M Baugh - University of California, San FranciscoJoel D Kaufman - University of WashingtonDavid Couper - University of North Carolina at Chapel HillNadia N Hansel - Johns Hopkins University
- Resource Type
- Journal article
- Publication Details
- Chronic obstructive pulmonary diseases, Vol.10(1), pp.102-111
- DOI
- 10.15326/jcopdf.2022.0350
- PMID
- 36599095
- PMCID
- PMC9995229
- ISSN
- 2372-952X
- eISSN
- 2372-952X
- Grant note
- HHSN268200900017C / NHLBI NIH HHS HHSN268200900016C / NHLBI NIH HHS HHSN268200900019C / NHLBI NIH HHS HHSN268200900020C / NHLBI NIH HHS HHSN268200900018C / NHLBI NIH HHS R01 ES023500 / NIEHS NIH HHS U24 HL141762 / NHLBI NIH HHS U01 HL137880 / NHLBI NIH HHS HHSN268200900014C / NHLBI NIH HHS HHSN268200900015C / NHLBI NIH HHS HHSN268200900013C / NHLBI NIH HHS R01ES023500 / NIEHS NIH HHS
- Language
- English
- Date published
- 01/04/2023
- Academic Unit
- Pulmonary, Critical Care, and Occupational Medicine; ICTS; Internal Medicine
- Record Identifier
- 9984361560402771
Metrics
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