An 8-Year Longitudinal Analysis of Physical Activity and Bone Strength From Adolescence to Emerging Adulthood: The Iowa Bone Development Study

Kristen M Metcalf; Elena M Letuchy; Steven M Levy; Kathleen F Janz

doi:10.1123/pes.2019-0090

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An 8-Year Longitudinal Analysis of Physical Activity and Bone Strength From Adolescence to Emerging Adulthood: The Iowa Bone Development Study

Journal article

Open access

Peer reviewed

An 8-Year Longitudinal Analysis of Physical Activity and Bone Strength From Adolescence to Emerging Adulthood: The Iowa Bone Development Study

Kristen M Metcalf, Elena M Letuchy, Steven M Levy and Kathleen F Janz

Pediatric exercise science, Vol.32(1), pp.58-64

02/01/2020

DOI: 10.1123/pes.2019-0090

PMCID: PMC7214197

PMID: 31896075

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https://www.ncbi.nlm.nih.gov/pmc/articles/7214197View

Open Access

Abstract

Most pediatric physical activity and bone health research has focused on the period immediately around puberty; few have addressed bone structural strength outcomes. This study assessed the magnitude and consistency of the longitudinal relationships between device-measured vigorous-intensity physical activity (VPA) and structural bone strength outcomes across adolescence to emerging adulthood. Participants with 3 to 5 bone scans between the age of 11 and 19 years were studied (N = 439, 220 females, 1838 records). Dual-energy X-ray absorptiometry scans of the hip (hip structural analysis) and peripheral quantitative computed tomography scans of the tibia were obtained. Outcomes included femoral neck section modulus, femoral neck cross-sectional area, tibial Bone Strength Index, and tibial torsion strength (polar Strength Strain Index). Sex-specific bone mixed growth models were developed using biological age (chronological age - age at peak height velocity) as the time variable, and height, weight, and device-measured VPA as time-varying covariates. Models also included the VPA-biological age interaction. Individual-centered VPA and the VPA-biological age interaction were significantly, positively associated (P < .05) with Bone Strength Index, polar Strength Strain Index, section modulus, and cross-sectional area in males and females, indicating accumulative effects of VPA throughout maturation and beyond. Bone remains responsive to the mechanical loading of physical activity throughout adolescence and into emerging adulthood. Attention should be placed on promoting bone-strengthening physical activity after the prepubertal years when adult exercise patterns are likely formed.

Absorptiometry, Photon

Adolescent

Bone Density

Bone Development

Child

Exercise

Female

Femur Neck - diagnostic imaging

Humans

Iowa

Longitudinal Studies

Male

Reference Values

Young Adult

Details

Title: Subtitle: An 8-Year Longitudinal Analysis of Physical Activity and Bone Strength From Adolescence to Emerging Adulthood: The Iowa Bone Development Study
Creators: Kristen M Metcalf - University of Iowa
Elena M Letuchy - University of Iowa
Steven M Levy - University of Iowa
Kathleen F Janz - University of Iowa
Resource Type: Journal article
Publication Details: Pediatric exercise science, Vol.32(1), pp.58-64
DOI: 10.1123/pes.2019-0090
PMID: 31896075
PMCID: PMC7214197
NLM abbreviation: Pediatr Exerc Sci
ISSN: 0899-8493
eISSN: 1543-2920
Grant note: M01 RR000059 / NCRR NIH HHS U54 TR001013 / NCATS NIH HHS R01 DE009551 / NIDCR NIH HHS U01 DE028522 / NIDCR NIH HHS UL1 RR024979 / NCRR NIH HHS R01 DE012101 / NIDCR NIH HHS UL1 TR000442 / NCATS NIH HHS R56 DE012101 / NIDCR NIH HHS
Language: English
Date published: 02/01/2020
Academic Unit: Preventive and Community Dentistry; Epidemiology; Health, Sport, and Human Physiology
Record Identifier: 9984367740502771

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