Journal article
An Acoustofluidic Micromixer via Bubble Inception and Cavitation from Microchannel Sidewalls
Analytical chemistry (Washington), Vol.86(10), pp.5083-5088
05/20/2014
DOI: 10.1021/ac5007798
PMCID: PMC4033639
PMID: 24754496
Abstract
During
the deep reactive ion etching process, the sidewalls of
a silicon mold feature rough wavy structures, which can be transferred
onto a polydimethylsiloxane (PDMS) microchannel through the soft lithography
technique. In this article, we utilized the wavy structures of PDMS
microchannel sidewalls to initiate and cavitate bubbles in the presence
of acoustic waves. Through bubble cavitation, this acoustofluidic
approach demonstrates fast, effective mixing in microfluidics. We
characterized its performance by using viscous fluids such as poly(ethylene
glycol) (PEG). When two PEG solutions with a resultant viscosity 54.9
times higher than that of water were used, the mixing efficiency was
found to be 0.92, indicating excellent, homogeneous mixing. The acoustofluidic
micromixer presented here has the advantages of simple fabrication,
easy integration, and capability to mix high-viscosity fluids (Reynolds
number: ∼0.01) in less than 100 ms.
Details
- Title: Subtitle
- An Acoustofluidic Micromixer via Bubble Inception and Cavitation from Microchannel Sidewalls
- Creators
- Adem Ozcelik - Pennsylvania State UniversityDaniel Ahmed - Pennsylvania State UniversityYuliang Xie - Pennsylvania State UniversityNitesh Nama - Pennsylvania State UniversityZhiguo Qu - Xi'an Jiaotong UniversityAhmad Ahsan Nawaz - Pennsylvania State UniversityTony Jun Huang - Pennsylvania State University
- Resource Type
- Journal article
- Publication Details
- Analytical chemistry (Washington), Vol.86(10), pp.5083-5088
- Publisher
- American Chemical Society
- DOI
- 10.1021/ac5007798
- PMID
- 24754496
- PMCID
- PMC4033639
- ISSN
- 0003-2700
- eISSN
- 1520-6882
- Grant note
- DOI: 10.13039/100000052, name: NIH Office of the Director, award: 1DP2OD007209-01; DOI: 10.13039/100000179, name: NSF Office of the Director, award: DMR-0820404
- Language
- English
- Date published
- 05/20/2014
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering
- Record Identifier
- 9984197013002771
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