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An Atypical Case of Extrapulmonary Sarcoidosis
Journal article   Open access   Peer reviewed

An Atypical Case of Extrapulmonary Sarcoidosis

Likhita Shaik, Madeleine Wagner Sherer and Michael T Rhodes
Curēus (Palo Alto, CA), Vol.14(12), e32164
12/03/2022
DOI: 10.7759/cureus.32164
PMID: 36601213
url
https://doi.org/10.7759/cureus.32164View
Published (Version of record) Open Access

Abstract

Sarcoidosis is an idiopathic, inflammatory condition that affects nearly all organs in the body. Lungs are the most frequent and among the earliest sites for detecting it. The most common extrapulmonary manifestations involve the ophthalmic, cardiac, nervous, reticuloendothelial, cutaneous, hepatosplenic, and renal systems. These extrapulmonary manifestations of sarcoid may be misdiagnosed in the absence of the classical pulmonary features, given the high overlap of features with other chronic immunologic diseases. The diagnostic workup to differentiate sarcoid from other similar conditions is extensive, amongst which histology remains a gold standard tool for the diagnosis. Our patient presented with a chronic history of multiple vague complaints including nausea, vomiting, progressive malaise, vision changes, and weight loss. After extensive workup, a diagnosis of sarcoidosis along with multiple rare extrapulmonary involvements was made. The authors highlight essential implications including primary practice goals to avoid misdiagnosis or missed sarcoid diagnoses thus helping improve clinical outcomes in similar populations.
 Medical Education Family/General Practice Pulmonology

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