Journal article
An Evaluation of Sexually Transmitted Infection and Odds of Preterm or Early-Term Birth Using Propensity Score Matching
Sexually transmitted diseases, Vol.46(6), pp.389-394
06/2019
DOI: 10.1097/OLQ.0000000000000985
PMID: 30762719
Abstract
Few studies have examined the relationship between sexually transmitted infections (STIs) and preterm birth (<37 weeks gestation) by subtype (<32 weeks, 32-36 weeks, spontaneous, provider-initiated). Here, we evaluate the odds of preterm (by subtype) and early-term (37 and 38 weeks gestation) birth in women with an STI compared with a propensity score-matched reference population.
The sample was selected from California births in 2007 to 2012. Sexually transmitted infection was defined as a maternal diagnosis of chlamydia, gonorrhea, or syphilis in the birth certificate or hospital discharge record. A reference sample of women without an STI was selected using exact propensity score matching on maternal factors. Odds of preterm and early-term birth were calculated.
Sixteen thousand three hundred twelve women were identified as having an STI during pregnancy and an exact propensity score-matched control was identified for 97.2% (n = 15,860). Women with an indication of syphilis during pregnancy were at 1.6 times higher odds of having a preterm birth and, in particular, at elevated odds of a birth less than 32 weeks due to preterm premature rupture of the membranes or provider-initiated birth (odds ratios 4.0-4.2). Women with gonorrhea were at increased odds of a preterm birth, a birth less than 32 weeks, or an early-term birth (odds ratios 1.2-1.8). Chlamydia did not raise the odds of either a preterm or early-term birth.
Gonorrhea and syphilis increased the odds of a preterm birth. Gonorrhea also increased the odds of an early-term birth. Chlamydia did not raise the odds of an early birth.
Details
- Title: Subtitle
- An Evaluation of Sexually Transmitted Infection and Odds of Preterm or Early-Term Birth Using Propensity Score Matching
- Creators
- Rebecca J BaerChristina D ChambersKelli K Ryckman - Departments of Epidemiology and Pediatrics, University of Iowa, Iowa City, IAScott P OltmanLarry RandLaura L Jelliffe-Pawlowski
- Resource Type
- Journal article
- Publication Details
- Sexually transmitted diseases, Vol.46(6), pp.389-394
- Publisher
- United States
- DOI
- 10.1097/OLQ.0000000000000985
- PMID
- 30762719
- ISSN
- 0148-5717
- eISSN
- 1537-4521
- Language
- English
- Date published
- 06/2019
- Academic Unit
- Stead Family Department of Pediatrics; Epidemiology
- Record Identifier
- 9983995013002771
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