Journal article
An In Vitro Model System Used To Study Adherence and Invasion of Francisella tularensis Live Vaccine Strain in Nonphagocytic Cells
Infection and immunity, Vol.75(6), pp.3178-3182
06/2007
DOI: 10.1128/IAI.01811-06
PMCID: PMC1932879
PMID: 17339345
Abstract
In observing
Francisella tularensis
interactions with nonphagocytic cell lines in vitro, we noted significant adherence, invasion, and intracellular growth of the bacteria within these cells.
F. tularensis
live vaccine strain invasion of nonprofessional phagocytic cells is inhibited by cytochalasin D and nocodazole, suggesting that both the actin and microtubule cytoskeletons are important for invasion.
Details
- Title: Subtitle
- An In Vitro Model System Used To Study Adherence and Invasion of Francisella tularensis Live Vaccine Strain in Nonphagocytic Cells
- Creators
- Stephen R Lindemann - Department of Microbiology, Roy J. and Lucille A. Carver School of Medicine, University of Iowa, Iowa City, Iowa 52242Molly K McLendon - Department of Microbiology, Roy J. and Lucille A. Carver School of Medicine, University of Iowa, Iowa City, Iowa 52242Michael A Apicella - Department of Microbiology, Roy J. and Lucille A. Carver School of Medicine, University of Iowa, Iowa City, Iowa 52242Bradley D Jones - Department of Microbiology, Roy J. and Lucille A. Carver School of Medicine, University of Iowa, Iowa City, Iowa 52242
- Resource Type
- Journal article
- Publication Details
- Infection and immunity, Vol.75(6), pp.3178-3182
- DOI
- 10.1128/IAI.01811-06
- PMID
- 17339345
- PMCID
- PMC1932879
- NLM abbreviation
- Infect Immun
- ISSN
- 0019-9567
- eISSN
- 1098-5522
- Publisher
- American Society for Microbiology
- Language
- English
- Date published
- 06/2007
- Academic Unit
- Microbiology and Immunology; Internal Medicine
- Record Identifier
- 9984083268302771
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