An Open Resource for Non-human Primate Optogenetics

Sebastien Tremblay; Leah Acker; Arash Afraz; Daniel L. Albaugh; Hidetoshi Amita; Ariana R. Andrei; Alessandra Angelucci; Amir Aschner; Puiu F. Balan; Michele A. Basso; Giacomo Benvenuti; Martin O. Bohlen; Michael J. Caiola; Roberto Calcedo; James Cavanaugh; Yuzhi Chen; Spencer Chen; Mykyta M. Chernov; Andrew M. Clark; Ji Dai; Samantha R. Debes; Karl Deisseroth; Robert Desimone; Valentin Dragoi; Seth W. Egger; Mark A. G. Eldridge; Hala G. El-Nahal; Francesco Fabbrini; Frederick Federer; Christopher R. Fetsch; Michel G. Fortuna; Robert M. Friedman; Naotaka Fujii; Alexander Gail; Adriana Galvan; Supriya Ghosh; Marc Alwin Gieselmann; Roberto A. Gulli; Okihide Hikosaka; Eghbal A. Hosseini; Xing Hu; Janina Huer; Ken-ichi Inoue; Roger Janz; Mehrdad Jazayeri; Rundong Jiang; Niansheng Ju; Kohitij Kar; Carsten Klein; Adam Kohn; Misako Komatsu; Kazutaka Maeda; Julio C. Martinez-Trujillo; Masayuki Matsumoto; John H. R. Maunsell; Diego Mendoza-Halliday; Ilya E. Monosov; Ross S. Muers; Lauri Nurminen; Michael Ortiz-Rios; Daniel J. O'Shea; Stephane Palfi; Christopher Petkov; Sorin Pojoga; Rishi Rajalingham; Charu Ramakrishnan; Evan D. Remington; Cambria Revsine; Anna W. Roe; Philip N. Sabes; Richard C. Saunders; Hansjorg Scherberger; Michael C. Schmid; Wolfram Schult; Eyal Seidemann; Yann-Suhan Senova; Michael N. Shadlen; David L. Sheinberg; Caitlin Siu; Yoland Smith; Selina S. Solomon; Marc A. Sommer; John L. Spudich; William R. Stauffer; Masahiko Takada; Shiming Tang; Alexander Thiele; Stefan Treue; Wim Vanduffel; Rufin Vogels; Matthew P. Whitmire; Thomas Wichmann; Robert H. Wurtz; Haoran Xu; Azadeh Yazdan-Shahmorad; Krishna Shenoy; James J. DiCarlo; Michael L. Pla

doi:10.1016/j.neuron.2020.09.027

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An Open Resource for Non-human Primate Optogenetics

Journal article

Open access

Peer reviewed

An Open Resource for Non-human Primate Optogenetics

Sebastien Tremblay, Leah Acker, Arash Afraz, Daniel L. Albaugh, Hidetoshi Amita, Ariana R. Andrei, Alessandra Angelucci, Amir Aschner, Puiu F. Balan, Michele A. Basso, …

Neuron (Cambridge, Mass.), Vol.108(6), pp.1075-1090.e6

12/23/2020

DOI: 10.1016/j.neuron.2020.09.027

PMCID: PMC7962465

PMID: 33080229

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Abstract

Optogenetics has revolutionized neuroscience in small laboratory animals, but its effect on animal models more closely related to humans, such as non-human primates (NHPs), has been mixed. To make evidence-based decisions in primate optogenetics, the scientific community would benefit from a centralized database listing all attempts, successful and unsuccessful, of using optogenetics in the primate brain. We contacted members of the community to ask for their contributions to an open science initiative. As of this writing, 45 laboratories around the world contributed more than 1,000 injection experiments, including precise details regarding their methods and outcomes. Of those entries, more than half had not been published. The resource is free for everyone to consult and contribute to on the Open Science Framework website. Here we review some of the insights from this initial release of the database and discuss methodological considerations to improve the success of optogenetic experiments in NHPs.

Life Sciences & Biomedicine

Neurosciences

Neurosciences & Neurology

Science & Technology

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Title: Subtitle: An Open Resource for Non-human Primate Optogenetics
Creators: Sebastien Tremblay - University of Pennsylvania
Leah Acker - McGovern Institute for Brain Research
Arash Afraz - National Institutes of Health
Daniel L. Albaugh - Emory University
Hidetoshi Amita - National Institutes of Health
Ariana R. Andrei - The University of Texas Health Science Center at Houston
Alessandra Angelucci - University of Utah
Amir Aschner - Albert Einstein College of Medicine
Puiu F. Balan - KU Leuven
Michele A. Basso - University of California, Los Angeles
Giacomo Benvenuti - The University of Texas at Austin
Martin O. Bohlen - Duke University
Michael J. Caiola - Emory University
Roberto Calcedo - University of Pennsylvania
James Cavanaugh - National Institutes of Health
Yuzhi Chen - The University of Texas at Austin
Spencer Chen - The University of Texas at Austin
Mykyta M. Chernov - Oregon Health & Science University
Andrew M. Clark - University of Utah
Ji Dai - Chinese Academy of Sciences
Samantha R. Debes - The University of Texas Health Science Center at Houston
Karl Deisseroth - Stanford University
Robert Desimone - McGovern Institute for Brain Research
Valentin Dragoi - The University of Texas Health Science Center at Houston
Seth W. Egger - McGovern Institute for Brain Research
Mark A. G. Eldridge - National Institutes of Health
Hala G. El-Nahal - Duke University
Francesco Fabbrini - KU Leuven
Frederick Federer - University of Utah
Christopher R. Fetsch - Johns Hopkins University
Michel G. Fortuna - German Primate Center
Robert M. Friedman - Oregon Health & Science University
Naotaka Fujii - RIKEN Center for Brain Science
Alexander Gail - University of Göttingen
Adriana Galvan - Emory University
Supriya Ghosh - University of Chicago
Marc Alwin Gieselmann - Newcastle University
Roberto A. Gulli - Columbia University
Okihide Hikosaka - National Institutes of Health
Eghbal A. Hosseini - McGovern Institute for Brain Research
Xing Hu - Emory University
Janina Huer - German Primate Center
Ken-ichi Inoue - Kyoto University
Roger Janz - The University of Texas Health Science Center at Houston
Mehrdad Jazayeri - McGovern Institute for Brain Research
Rundong Jiang - Peking University
Niansheng Ju - Peking University
Kohitij Kar - McGovern Institute for Brain Research
Carsten Klein - Max Planck Society
Adam Kohn - Yeshiva University
Misako Komatsu - RIKEN Center for Brain Science
Kazutaka Maeda - National Institutes of Health
Julio C. Martinez-Trujillo - Western University
Masayuki Matsumoto - University of Tsukuba
John H. R. Maunsell - University of Chicago
Diego Mendoza-Halliday - McGovern Institute for Brain Research
Ilya E. Monosov - Washington University in St. Louis
Ross S. Muers - Newcastle University
Lauri Nurminen - University of Utah
Michael Ortiz-Rios - Newcastle University
Daniel J. O'Shea - Stanford University
Stephane Palfi - Université Paris Cité
Christopher Petkov - Newcastle University
Sorin Pojoga - The University of Texas Health Science Center at Houston
Rishi Rajalingham - McGovern Institute for Brain Research
Charu Ramakrishnan - Stanford University
Evan D. Remington - McGovern Institute for Brain Research
Cambria Revsine - University of Pennsylvania
Anna W. Roe - Zhejiang University
Philip N. Sabes - University of California, San Francisco
Richard C. Saunders - National Institutes of Health
Hansjorg Scherberger - University of Göttingen
Michael C. Schmid - Newcastle University
Wolfram Schult - University of Cambridge
Eyal Seidemann - The University of Texas at Austin
Yann-Suhan Senova - Université Paris Cité
Michael N. Shadlen - Columbia University
David L. Sheinberg - Brown University
Caitlin Siu - University of Utah
Yoland Smith - Emory University
Selina S. Solomon - Albert Einstein College of Medicine
Marc A. Sommer - Duke University
John L. Spudich - The University of Texas Health Science Center at Houston
William R. Stauffer - University of Pittsburgh
Masahiko Takada - Kyoto University
Shiming Tang - Peking University
Alexander Thiele - Newcastle University
Stefan Treue - University of Göttingen
Wim Vanduffel - KU Leuven
Rufin Vogels - KU Leuven
Matthew P. Whitmire - The University of Texas at Austin
Thomas Wichmann - Emory University
Robert H. Wurtz - National Institutes of Health
Haoran Xu - McGovern Institute for Brain Research
Azadeh Yazdan-Shahmorad - University of California, San Francisco
Krishna Shenoy - Stanford University
James J. DiCarlo - McGovern Institute for Brain Research
Michael L. Pla - University of Pennsylvania
Resource Type: Journal article
Publication Details: Neuron (Cambridge, Mass.), Vol.108(6), pp.1075-1090.e6
Publisher: Elsevier
DOI: 10.1016/j.neuron.2020.09.027
PMID: 33080229
PMCID: PMC7962465
ISSN: 0896-6273
eISSN: 1097-4199
Number of pages: 23
Grant note: 172644KYSB20170004 / Chinese Academy of Sciences International Partnership Program Howard Hughes Medical Institute American Heart Association Western States Affiliate Postdoctoral Fellowship; American Heart Association NSF Graduate Research Fellowship; National Science Foundation (NSF) ZIAMH002958 / Intramural Research Program of the NIMH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH) NINDS-NS078127 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA National Basic Research Program of China SCHM 2806/1-1 / DFG Emmy Noether grant; German Research Foundation (DFG) P50MH094258 / NIH Caltech Conte Center; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA McKnight Foundation Wellcome Trust Investigator Award; Wellcome Trust R01EY016454 / NEI; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI) Japan Science and Technology Agency; Japan Science & Technology Agency (JST) 2017120 / Youth Innovation Promotion Association CAS 325380; 543045 / Simons Foundation Collaboration on the Global Brain awards JP19dm0207001 / Brain/MINDS P50 NS098685 / NIH/NINDS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) R01 EY026812; R01 EY019743; BRAIN U01 NS099702; R01 EY013962; R21 EY024516; R01EY029666; EY026240; R01EY005911; EY022853; R01 R01NS078127; EY029374 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA P51 OD011132 / NIH/ORIP R01MH110594; R01MH116937 / National Institute of Mental Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH) Canada Banting Fellowship C14/17/109 / internal KU Leuven funds UCSF Neuroscience Imaging Center 31600870 / National Natural Science Foundation of China; National Natural Science Foundation of China (NSFC) 785907 / European Union Horizon 2020 Framework Program for Research and Innovation NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Japan Agency for Medical Research and Development; Japan Agency for Medical Research and Development (AMED) 1ZIAEY000415-16; R01 EY11378 / National Eye Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI) OptoVision 637638; 293549 / European Research Council; European Research Council (ERC); European Commission U01NS099720 / NIH-BRAIN Dr. Regina Casper Stanford Graduate Fellowship 8DP1HD075623 / NIH Director's Pioneer Award; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Fondation de France NIH NIDCD; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Deafness & Other Communication Disorders (NIDCD) 17H06034 / KA-KENHI; Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT); Japan Society for the Promotion of Science; Grants-in-Aid for Scientific Research (KAKENHI) Medical Research Council; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) WGLSAW-2014-DPZ-1 / Leibniz Association 095495 / Wellcome Trust National Natural Science Foundation of China; National Natural Science Foundation of China (NSFC) IOS 1755431 / NSF; National Science Foundation (NSF) Charles E. Kaufman Foundation W911NF-14-2-0013 / DARPA BTO "NeuroFAST'' award Fonds voor Wetenschappelijk Onderzoek Vlaanderen; FWO Oxford Biomedica (Oxford, UK) ARSC (France) Ministry of Education, Science, Sports, Culture, and Technology of Japan; Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT) Research Foundation Flanders (FWO-Flanders); FWO FOR 1847 / German Research Foundation; German Research Foundation (DFG) 1U01MH109146 / BRAIN Initiative Stavros Niarchos Foundation/Research to Prevent Blindness N66001-10-C-2010; NIH-EY014681 / Defense Advanced Research Projects Agency (DARPA) Biological Technology Office (BTO) "REPAIR'' award European Research Council Consolidator Award (MECHIDENT) N66001-10-C-2010 / Defense Advanced Research Projects Agency (DARPA) Reorganization and Plasticity to Accelerate Injury Recovery (REPAIR); United States Department of Defense; Defense Advanced Research Projects Agency (DARPA) Fight for Sight
Language: English
Date published: 12/23/2020
Academic Unit: Iowa Neuroscience Institute; Neurosurgery; Otolaryngology
Record Identifier: 9984360006302771

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