Journal article
An RFLP for glycophorin A (MN) is in linkage disequilibrium with MN and Ss
Cytogenetic and genome research, Vol.47(3), pp.149-151
1988
DOI: 10.1159/000132534
PMID: 2897896
Abstract
Using a cDNA for glycophorin A (MN), we screened 10 unrelated Caucasians using 22 restriction enzymes for RFLPs. A common Stul RFLP was identified and shown to be in marked linkage disequilibrium with both the MN and Ss blood-group antigens in a larger group of unrelated Caucasians. This provides a DNA marker for a locus that has been of major importance in genetic and population studies. The demonstrated disequilibrium will prove useful in localizing the gene for glycophorin B and in studies of genetic and physical distances on human chromosomes.
Details
- Title: Subtitle
- An RFLP for glycophorin A (MN) is in linkage disequilibrium with MN and Ss
- Creators
- J.C MurrayK.H BuetowR.E FerrellP.D SiebergM Fukuda
- Resource Type
- Journal article
- Publication Details
- Cytogenetic and genome research, Vol.47(3), pp.149-151
- DOI
- 10.1159/000132534
- PMID
- 2897896
- NLM abbreviation
- Cytogenet Genome Res
- ISSN
- 1424-8581
- eISSN
- 1424-859X
- Publisher
- Basel, Switzerland
- Number of pages
- 3
- Language
- English
- Date published
- 1988
- Academic Unit
- Anatomy and Cell Biology; Stead Family Department of Pediatrics; Epidemiology; Pediatric Dentistry; Craniofacial Anomalies Research Center; Dental Research
- Record Identifier
- 9984025328202771
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