An analysis of body weight and hemodialysis adequacy based on the urea reduction ratio... including commentary by Brunt H with author response

Y. Hayajneh; Kennith R. Culp; M. Flanigan

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An analysis of body weight and hemodialysis adequacy based on the urea reduction ratio... including commentary by Brunt H with author response

Journal article

Peer reviewed

An analysis of body weight and hemodialysis adequacy based on the urea reduction ratio... including commentary by Brunt H with author response

Y. Hayajneh, Kennith R. Culp and M. Flanigan

ANNA Journal, Vol.26(4), pp.391-401

08/1999

PMID: 10838970

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Abstract

<p>The purpose of this study was to evaluate inadequate hemodialysis risk in patients with body weights in the upper quartile of a sample distribution using the urea reduction ratio (URR). Using a case-control design and a simple (n = 315) of hemodialysis (HD) patients, postdialysis weights were divided into quartiles based with a cut-off value at the upper quartile, which was equal to >/= 81 kilograms (kg). The dichotomous outcome, URR >/= 65% and URR /= 81 kg group were given more dialysis session time in minutes and used higher efficiency dialyzers as indicated by the coefficient of ultrafiltration (KUf), yet were more likely to have URRs /= 81 kg group were given more dialysis session time in minutes and used higher efficiency dialyzers as indicated by the coefficient of ultrafiltration (KUf), yet were more likely to have URRs 81 kg experienced an increased risk of inadequate dialysis when compared to all others (OR 4.02, 95% CI [confidence interval] 2.217-7.29). A postdialysis weight >/= 81 kg increased the risk of inadequate dialysis for patients in this sample. This effect was confounded by a dialysis time x weight interaction term. Also, women were found to have a lower inadequate dialysis risk compared to men after adjusting for weight classification. We, therefore, conclude that patients who weigh >/= 81 kg may experience inadequate dialysis despite longer, more efficient dialysis sessions. Longer dialysis sessions may benefit some patients, but the effect in larger patients may not be a uniform response.</p>

Nursing

Hemodialysis -- Evaluation

Urea

Body Weight

Treatment Outcomes -- Evaluation

Blood Urea Nitrogen

Blood Specimen Collection

Odds Ratio

Case Control Studies

Random Sample

Retrospective Design

Logistic Regression

Analysis of Variance

Analysis of Covariance

Human

Details

Title: Subtitle: An analysis of body weight and hemodialysis adequacy based on the urea reduction ratio... including commentary by Brunt H with author response
Creators: Y. Hayajneh
Kennith R. Culp
M. Flanigan
Resource Type: Journal article
Publication Details: ANNA Journal, Vol.26(4), pp.391-401
PMID: 10838970
NLM abbreviation: Anna J
ISSN: 8750-0779
Language: English
Date published: 08/1999
Academic Unit: Occupational and Environmental Health; Nursing; Internal Medicine
Record Identifier: 9983557455502771

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