Journal article
An automated all-in-one system for carbohydrate tracking, glucose monitoring, and insulin delivery
Journal of controlled release, Vol.343, pp.31-42
03/2022
DOI: 10.1016/j.jconrel.2022.01.001
PMID: 34998917
Abstract
Glycemic control through titration of insulin dosing remains the mainstay of diabetes mellitus treatment. Insulin therapy is generally divided into dosing with long- and short-acting insulin, where long-acting insulin provides basal coverage and short-acting insulin supports glycemic excursions associated with eating. The dosing of short-acting insulin often involves several steps for the user including blood glucose measurement and integration of potential carbohydrate loads to inform safe and appropriate dosing. The significant burden placed on the user for blood glucose measurement and effective carbohydrate counting can manifest in substantial effects on adherence. Through the application of computer vision, we have developed a smartphone-based system that is able to detect the carbohydrate load of food by simply taking a single image of the food and converting that information into a required insulin dose by incorporating a blood glucose measurement. Moreover, we report the development of comprehensive all-in-one insulin delivery systems that streamline all operations that peripheral devices require for safe insulin administration, which in turn significantly reduces the complexity and time required for titration of insulin. The development of an autonomous system that supports maximum ease and accuracy of insulin dosing will transform our ability to more effectively support patients with diabetes.
Details
- Title: Subtitle
- An automated all-in-one system for carbohydrate tracking, glucose monitoring, and insulin delivery
- Creators
- Hen-Wei Huang - Massachusetts Institute of TechnologySiheng Sean You - Brigham and Women's HospitalLuca Di Tizio - Massachusetts Institute of TechnologyCanchen Li - Massachusetts Institute of TechnologyErin Raftery - Brigham and Women's HospitalClaas Ehmke - Massachusetts Institute of TechnologyChristoph Steiger - Brigham and Women's HospitalJunwei Li - Brigham and Women's HospitalAdam Wentworth - Brigham and Women's HospitalIan Ballinger - Brigham and Women's HospitalDeclan Gwynne - Massachusetts Institute of TechnologyKewang Nan - Massachusetts Institute of TechnologyJia Y Liang - Massachusetts Institute of TechnologyJason Li - Brigham and Women's HospitalJames D Byrne - Massachusetts Institute of TechnologyJoy Collins - Massachusetts Institute of TechnologySiddartha Tamang - Massachusetts Institute of TechnologyKeiko Ishida - Massachusetts Institute of TechnologyFlorencia Halperin - Brigham and Women's HospitalGiovanni Traverso - Massachusetts Institute of Technology
- Resource Type
- Journal article
- Publication Details
- Journal of controlled release, Vol.343, pp.31-42
- DOI
- 10.1016/j.jconrel.2022.01.001
- PMID
- 34998917
- ISSN
- 0168-3659
- eISSN
- 1873-4995
- Language
- English
- Date published
- 03/2022
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiation Oncology
- Record Identifier
- 9984274856902771
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