An unusual association of Ménétrier's disease with a gastric bezoar

Karan Manoj Anandpara; Yashant Aswani; Priya Hira

doi:10.1136/bcr-2014-207087

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An unusual association of Ménétrier's disease with a gastric bezoar

Journal article

Open access

Peer reviewed

An unusual association of Ménétrier's disease with a gastric bezoar

Karan Manoj Anandpara, Yashant Aswani and Priya Hira

BMJ case reports, Vol.2015(feb16 1), pp.bcr2014207087-bcr2014207087

02/16/2015

DOI: 10.1136/bcr-2014-207087

PMCID: PMC4330415

PMID: 25687706

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Abstract

Ménétrier's disease is a rare protein-losing hypertrophic gastroenteropathy. While it still remains a medical curiosity, infection with Cytomegalovirus and Helicobacter pylori, and hormonal, congenital, dietary and neurogenic factors have been postulated as causative factors. We describe a case of a 14-year boy who presented with epigastric discomfort, vomiting, inability to gain weight and pedal oedema. Investigations revealed hypoproteinaemia without proteinuria and elevated faecal α-1-antitrypsin levels suggestive of protein-losing enteropathy. Imaging and endoscopic features demonstrated cerebriform gastric folds indicative of Ménétrier's disease. Infective, hormonal and neurogenic causes were ruled out in our patient. Surprisingly, the patient had a history of pica and an associated large gastric bezoar, which was ultimately removed surgically. An association of Ménétrier's disease with a bezoar has been reported only once previously. We thus add to the existing literature and highlight the plausible role of a bezoar as a causative factor in the pathogenesis of Ménétrier's disease due to its irritant nature.

Adolescent

Bezoars - complications

Bezoars - diagnostic imaging

Bezoars - surgery

Gastritis, Hypertrophic - complications

Humans

Male

Pica - complications

Stomach - diagnostic imaging

Stomach - surgery

Tomography, X-Ray Computed

Details

Title: Subtitle: An unusual association of Ménétrier's disease with a gastric bezoar
Creators: Karan Manoj Anandpara - Seth G S Medical College and KEM Hospital, Mumbai, Maharashtra, India.
Yashant Aswani - Seth G S Medical College and KEM Hospital, Mumbai, Maharashtra, India.
Priya Hira - Seth G S Medical College and KEM Hospital, Mumbai, Maharashtra, India.
Resource Type: Journal article
Publication Details: BMJ case reports, Vol.2015(feb16 1), pp.bcr2014207087-bcr2014207087
DOI: 10.1136/bcr-2014-207087
PMID: 25687706
PMCID: PMC4330415
ISSN: 1757-790X
eISSN: 1757-790X
Language: English
Date published: 02/16/2015
Academic Unit: Radiology
Record Identifier: 9984318699902771

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