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An update of cancer incidence in the Agricultural Health Study
Journal article   Open access   Peer reviewed

An update of cancer incidence in the Agricultural Health Study

Stella Koutros, Michael C R Alavanja, Jay H Lubin, Dale P Sandler, Jane A Hoppin, Charles F Lynch, Charles Knott, Aaron Blair and Laura E Beane Freeman
Journal of occupational and environmental medicine, Vol.52(11), pp.1098-1105
11/2010
DOI: 10.1097/JOM.0b013e3181f72b7c
PMCID: PMC3052640
PMID: 21063187

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Abstract

Our objective is to reevaluate cancer incidence among Agricultural Health Study participants. Standardized incidence ratios (SIRs) and relative standardized ratios were calculated. A significant excess of prostate cancer was seen for private and commercial applicators (SIR = 1.19, 95% CI 1.14, 1.25 and SIR = 1.28, 95% CI = 1.00, 1.61, respectively). Excesses were observed for lip cancer (SIR = 1.97, 95% CI = 1.02, 3.44) and multiple myeloma (SIR = 1.42, 95% CI = 1.00, 1.95) among private applicators from North Carolina and for marginal zone lymphoma among Iowa spouses (SIR = 2.34, 95% CI = 1.21, 4.09). Although lower rates of smoking and increased physical activity probably contribute to the lower overall cancer incidence, agricultural exposures including pesticides, viruses, bacteria, sunlight, and other chemicals may increase risks for specific cancer sites.
 Registries Spouses - statistics & numerical data Prospective Studies Occupational Exposure - adverse effects Humans Middle Aged Agricultural Workers' Diseases - epidemiology Male Incidence Air Pollutants, Occupational - adverse effects Neoplasms - chemically induced Adult Female Aged Pesticides - adverse effects North Carolina - epidemiology Neoplasms - epidemiology Agricultural Workers' Diseases - chemically induced

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