Journal article
Analysis of fasting antroduodenal manometry in children
Digestive diseases and sciences, Vol.41(11), pp.2195-2203
11/1996
DOI: 10.1007/BF02071400
PMID: 8943972
Abstract
Antroduodenal manometry has been used to determine the pathophysiology associated with signs and symptoms of gastrointestinal motility disorders. The diagnostic value of antroduodenal manomentry has been limited by the paucity of data from normal children. In this study, we compared antroduodenal manometry findings from 95 patients with symptoms suggesting a gastrointestinal motility disorder to 20 control children. Phase III of the migrating motor complex (MMC) was less frequent in patients (P<0.05), especially in those who required total parenteral nutrition (P<0.001), than in controls. Abnormal migration of phase III and short intervals between phase IIIs were more frequent in patients than in controls (P<0.01 andP<0.05, respectively). During phase II, persistent low-amplitude contractions and sustained tonic-phasic contraction were found only in parenteral-nutrition-dependent children. Short or prolonged duration of phase III, absence of phase I following phase III, tonic contractions during phase III, low amplitude of phase III contractions in a single recording site and clusters of contractions or prolonged propagating contractions during phase II were not more frequent in patients than in controls. We conclude that there are five manometric features having a clear association with pediatric gastrointestinal motility disorders: (1) absence of phase III of the MMC, (2) abnormal migration of phase III, (3) short intervals between phase III episodes, (4) persistent low-amplitude contractions, and (5) sustained tonic-phasic contractions.
Details
- Title: Subtitle
- Analysis of fasting antroduodenal manometry in children
- Creators
- Takeshi Tomomasa - Gunma UniversityCarlo DiLorenzo - Gunma UniversityAkihiro Morikawa - Gunma UniversityAliye UC - Gunma UniversityPaul E. Hyman - Gunma University
- Resource Type
- Journal article
- Publication Details
- Digestive diseases and sciences, Vol.41(11), pp.2195-2203
- DOI
- 10.1007/BF02071400
- PMID
- 8943972
- ISSN
- 0163-2116
- eISSN
- 1573-2568
- Language
- English
- Date published
- 11/1996
- Academic Unit
- Stead Family Department of Pediatrics; Radiation Oncology; Gastroenterology, Hepatology, Pancreatology, and Nutrition
- Record Identifier
- 9984312970902771
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