Journal article
Anatomic and Functional Changes Associated with Crossed Cerebellar Diaschisis in Chronic Brain Injured Subjects
Neurorehabilitation and neural repair, Vol.5(4), pp.219-227
12/1991
DOI: 10.1177/136140969100500404
Abstract
The anatomic and functional changes associated with crossed cerebellar diaschisis (CCD) were examined in chronic brain injured patients to determine if there is evidence that injury to a neuroanatomic tract, such as the corticopontocerebellar tract, could explain the cerebellar diaschisis, and to determine if arm movements would effect the CCD. Four brain injured patients and four normal subjects had MR scans and PET scans using fluorodeoxyglucose. The PET scans were obtained during rest and during left and right arm motor tasks. The PET scans were repeated after six months to determine the reproducibility of the scan findings.
Forty-one PET scans were analyzed. Significant crossed cerebellar diaschisis was present in all fourbrain injured patients. One control patient had crossed cerebellar diaschisis, but the cerebellar asymmetry was more subtle than noted in the brain injured patients. MR scans demonstrated atrophy of the cerebral peduncle ipsilateral to the major cerebral cortical injury. One patient had bilateral cerebral cortical and cerebral peduncle atrophy. These findings support the hypothesis that injury to the corticopontocerebellar tract may, in part, be responsible for crossed cerebellar diaschisis in chronic brain injured subjects. Key Words: Brain, injuries—Brain, radionuclide studies—Emission CT—Diaschisis—Degeneration, Wallerian.
Details
- Title: Subtitle
- Anatomic and Functional Changes Associated with Crossed Cerebellar Diaschisis in Chronic Brain Injured Subjects
- Creators
- Scott Perlman - UW Health University HospitalKatharine Blood - Department of Rehabilitation Medicine, University of Wisconsin, Hospital and ClinicsJoseph Sackett - University of Wisconsin Hospital and Clinics, Department of Radiology, 600 Highland Avenue, Madison, WI 53792, William S. Middleton Memorial Veteran's Hospital, 2500 Overlook Terrace, Madison, WI 53705Richard Balliet - Department of Rehabilitation Medicine, University of Wisconsin, Hospital and ClinicsJoAnne Lazarus - University of Wisconsin Department of Physical Education and DanceMichael Wilson - UW Health University HospitalJohn Sunderland - University of Wisconsin Department of Medical PhysicsRobert Nickles - University of Wisconsin Department of Medical Physics
- Resource Type
- Journal article
- Publication Details
- Neurorehabilitation and neural repair, Vol.5(4), pp.219-227
- Publisher
- Sage Publications
- DOI
- 10.1177/136140969100500404
- ISSN
- 1545-9683
- eISSN
- 1552-6844
- Language
- English
- Date published
- 12/1991
- Academic Unit
- Radiology; Physics and Astronomy; Radiation Oncology
- Record Identifier
- 9984313080102771
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