Anatomy of the Mediterranean Diet and Mortality Among Older Women with Frailty

Oleg Zaslavsky; Shira Zelber-Sagi; James M Shikany; Tonya Orchard; Robert Wallace; Linda Snetselaar; Lesley Tinker

doi:10.1080/21551197.2018.1496217

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Anatomy of the Mediterranean Diet and Mortality Among Older Women with Frailty

Journal article

Peer reviewed

Anatomy of the Mediterranean Diet and Mortality Among Older Women with Frailty

Oleg Zaslavsky, Shira Zelber-Sagi, James M Shikany, Tonya Orchard, Robert Wallace, Linda Snetselaar and Lesley Tinker

Journal of nutrition in gerontology and geriatrics, Vol.37(3-4), pp.269-281

10/02/2018

DOI: 10.1080/21551197.2018.1496217

PMCID: PMC6378120

PMID: 30118645

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Abstract

We examined individual components of the Mediterranean Diet (Med) and evaluated their relative contribution to mortality rates in older women with frailty. A sample (N = 10,431) included Women's Health Initiative Observational Study participants aged 65-84 y with complete frailty diagnostic criteria and dietary data. Frailty was assessed with modified Fried's criteria, and dietary data were collected through food frequency questionnaire. Over a mean follow-up of 12.4 y (range 3-21.0), 3,259 (31.2%) deaths occurred. Crude death rates demonstrated a decrease in mortality with higher intake of individual Med components. However, in the mutually adjusted models, most Med components on their own were not significantly associated with mortality. Exceptions were vegetables, nuts, and whole grains. A higher intake of vegetables, nuts, and whole grains were associated with a significantly decreased hazard of mortality, by 9% (P = 0.02), 13% (P < 0.001), and 17% (P < 0.001), respectively. The relative contribution of these components to diet mortality associations were 21%, 42%, and 57% for vegetables, nuts, and whole grains, respectively. Subgroup analyses by chronic morbidity, smoking status, or excluding women with early death did not substantially change these results.

Dietary pattern

longitudinal

nutrition

population

women's health initiative

Details

Title: Subtitle: Anatomy of the Mediterranean Diet and Mortality Among Older Women with Frailty
Creators: Oleg Zaslavsky - School of Nursing, University of Washington
Shira Zelber-Sagi - Faculty of Health Science and Social Welfare, University of Haifa
James M Shikany - Division of Preventive Medicine, University of Alabama
Tonya Orchard - College of Education and Human Ecology, Ohio State University
Robert Wallace - College of Public Health, University of Iowa
Linda Snetselaar - College of Public Health, University of Iowa
Lesley Tinker - Public Health Sciences, Fred Hutchinson Cancer Research Center
Resource Type: Journal article
Publication Details: Journal of nutrition in gerontology and geriatrics, Vol.37(3-4), pp.269-281
DOI: 10.1080/21551197.2018.1496217
PMID: 30118645
PMCID: PMC6378120
NLM abbreviation: J Nutr Gerontol Geriatr
ISSN: 2155-1197
eISSN: 2155-1200
Publisher: Taylor & Francis
Grant note: HHSN268201600018C; HHSN268201600001C; HHSN268201600002C; HHSN268201600002C; HHSN268201600004C / National Heart, Lung and Blood Institute, National Institutes of Health, U.S. Department of Health and Human Services
Language: English
Date published: 10/02/2018
Academic Unit: Epidemiology; Fraternal Order of Eagles Diabetes Research Center; Injury Prevention Research Center; Internal Medicine
Record Identifier: 9984215148002771

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