Journal article
Aneurysmal subarachnoid hemorrhage in patients under 35-years-old: A single-center experience
Clinical neurology and neurosurgery, Vol.115(6), pp.665-668
06/2013
DOI: 10.1016/j.clineuro.2012.07.016
PMID: 22858084
Abstract
Aneurysmal subarachnoid hemorrhage (SAH) is relatively uncommon in young adults. There is a paucity of data pertaining to the management of aneurysmal SAH in young patients, especially with endovascular therapy.
We reviewed all SAH patients under the age of 35 years treated at Jefferson Hospital for Neuroscience, Philadelphia, USA, from 2004 to 2009.
A total of 40 patients (15 males and 25 females) under the age of 35 were treated for aneurysmal SAH. The average patient age was 30 years (17–35 yo); 25 (62.5%) were smokers. Seventeen patients presented with a Hunt and Hess Grade I or II (42.5%), 20 with a Grade III (50%), and 3 with a Grade IV (7.5%). Thirty-two aneurysms (80%) were located in the anterior circulation and 8 (20%) in the posterior circulation. Thirty-five patients (87.5%) were treated with coil embolization versus 5 with craniotomy and clipping. The endovascular and microsurgical occlusion rates were 90.6% and 100%, respectively. There were no procedural complications with endovascular therapy. Of 35 patients undergoing endovascular treatment, 24 (68.6%) had excellent outcomes at time of discharge with a Glasgow outcome scale of 5. There were no deaths in the series. No patient experienced a rehemorrhage after endovascular treatment.
Smoking, female sex, and anterior circulation aneurysms are highly prevalent in young adults with SAH. Endovascular treatment resulted in an overall favorable outcome with no rehemorrhages in patients under the age of 35 years. Our results suggest that endovascular therapy is a reasonable treatment for young patients with SAH.
Details
- Title: Subtitle
- Aneurysmal subarachnoid hemorrhage in patients under 35-years-old: A single-center experience
- Creators
- Nohra Chalouhi - Department of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA, United StatesSonia Teufack - Department of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA, United StatesSid Chandela - Department of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA, United StatesRichard Dalyai - Department of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA, United StatesStavropoula Tjoumakaris - Department of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA, United StatesDavid M Hasan - Department of Neurosurgery, University of Iowa, Iowa City, Iowa, USAAaron S Dumont - Department of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA, United StatesL. Fernando Gonzalez - Department of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA, United StatesRobert H Rosenwasser - Department of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA, United StatesPascal M Jabbour - Department of Neurological Surgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA, United States
- Resource Type
- Journal article
- Publication Details
- Clinical neurology and neurosurgery, Vol.115(6), pp.665-668
- Publisher
- Elsevier B.V
- DOI
- 10.1016/j.clineuro.2012.07.016
- PMID
- 22858084
- ISSN
- 0303-8467
- eISSN
- 1872-6968
- Language
- English
- Date published
- 06/2013
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Neurosurgery; Otolaryngology
- Record Identifier
- 9984040237802771
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