Angioplasty and stenting for atherosclerotic intracranial stenosis: rationale for a randomized clinical trial

Colin P Derdeyn; Marc I Chimowitz

doi:10.1016/j.nic.2007.05.001

Back

Angioplasty and stenting for atherosclerotic intracranial stenosis: rationale for a randomized clinical trial

Journal article

Peer reviewed

Angioplasty and stenting for atherosclerotic intracranial stenosis: rationale for a randomized clinical trial

Colin P Derdeyn and Marc I Chimowitz

Neuroimaging clinics of North America, Vol.17(3), pp.355-363

08/2007

DOI: 10.1016/j.nic.2007.05.001

PMCID: PMC2040119

PMID: 17826637

Files and links (1)

url

http://doi.org/10.1016/j.nic.2007.05.001View

Open Access

Abstract

Atherosclerotic disease of the major intracranial arteries is a frequent cause of stroke. In addition, many patients who have symptomatic intracranial stenosis are at very high risk for recurrent stroke. Preliminary studies suggest that angioplasty and stenting may reduce the risk of stroke in patients who have severe stenosis of intracranial arteries. Data for angioplasty and stenting, however, consist of case series; no randomized studies have been completed to date. This article reviews these data and discusses the rationale for a randomized trial of angioplasty and stenting versus best medical management for patients who have symptomatic intracranial stenosis.

Carotid Arteries - drug effects

Intracranial Arteriosclerosis - drug therapy

Cerebral Arteries - surgery

Constriction, Pathologic - therapy

Humans

Carotid Stenosis - drug therapy

Carotid Stenosis - therapy

Anticoagulants - therapeutic use

Angioplasty - methods

Randomized Controlled Trials as Topic

Cerebral Arteries - drug effects

Brain - blood supply

Constriction, Pathologic - drug therapy

Constriction, Pathologic - surgery

Intracranial Arteriosclerosis - surgery

Cerebral Arteries - pathology

Carotid Arteries - surgery

Carotid Arteries - pathology

Intracranial Arteriosclerosis - therapy

Stents

Carotid Stenosis - surgery

Details

Title: Subtitle: Angioplasty and stenting for atherosclerotic intracranial stenosis: rationale for a randomized clinical trial
Creators: Colin P Derdeyn - Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway Blvd, St. Louis, MO 63110, USA. derdeync@wustl.edu
Marc I Chimowitz
Resource Type: Journal article
Publication Details: Neuroimaging clinics of North America, Vol.17(3), pp.355-363
DOI: 10.1016/j.nic.2007.05.001
PMID: 17826637
PMCID: PMC2040119
NLM abbreviation: Neuroimaging Clin N Am
ISSN: 1052-5149
eISSN: 1557-9867
Publisher: United States
Grant note: R01 NS051688 / NINDS NIH HHS R01 NS051631-02 / NINDS NIH HHS K24 NS050307 / NINDS NIH HHS R01 NS051631 / NINDS NIH HHS R01 NS036643 / NINDS NIH HHS
Language: English
Date published: 08/2007
Academic Unit: Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
Record Identifier: 9984020791402771

Metrics

29 Record Views

53 Times Cited - Web of Science