Journal article
Annularins A-H: New polyketide metabolites from the freshwater aquatic fungus Annulatascus triseptatus
Journal of natural products (Washington, D.C.), Vol.66(10), pp.1302-1306
2003
DOI: 10.1021/np030225y
PMID: 14575427
Abstract
Eight new polyketide metabolites, annularins A-H (1-8), along with the known compound (-)-(S)-p-hydroxyphenyllactic acid, were isolated from the organic extracts of the freshwater fungus Annulatascus triseptatus. Compounds 1-6 are 3,4,5-trisubstituted α-pyrones, and the fused bicyclic pyrone-furanone system in annularin F (6) has not been reported previously among natural products. Compounds 7 and 8 are 3,4-disubstituted α,β-unsaturated γ-lactones. Annularins A (1), B (2), C (3), and F (6) exhibited antibacterial activity.
Details
- Title: Subtitle
- Annularins A-H: New polyketide metabolites from the freshwater aquatic fungus Annulatascus triseptatus
- Creators
- CHEN LI - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, United StatesMeaghan V Nitka - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, United StatesJames B Gloer - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, United StatesJinx Campbell - Department of Plant Biology, University of Illinois, Urbana, Illinois 61801, United StatesCarol A Shearer - Department of Plant Biology, University of Illinois, Urbana, Illinois 61801, United States
- Resource Type
- Journal article
- Publication Details
- Journal of natural products (Washington, D.C.), Vol.66(10), pp.1302-1306
- Publisher
- American Society of Pharmacognosy
- DOI
- 10.1021/np030225y
- PMID
- 14575427
- ISSN
- 0163-3864
- eISSN
- 1520-6025
- Language
- English
- Date published
- 2003
- Academic Unit
- Chemistry
- Record Identifier
- 9984216578102771
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