Journal article
Antenatal steroids and thyroid hormone function in preterm infants
Journal of perinatology, Vol.38(11), pp.1466-1470
11/01/2018
DOI: 10.1038/s41372-018-0225-5
PMID: 30206348
Abstract
Background Antenatal steroids (ANS) are used widely for women at risk of preterm delivery. Evidence on the effects of ANS on thyroid hormone function in preterm infants is limited.
Objectives To determine effects of ANS on thyroid hormone function in preterm infants.
Methods A retrospective cohort study of preterm infants born before 30 weeks of gestation. Infants were divided into no ANS, partial ANS, and complete ANS groups. Thyroid function tests at day of life 30 were compared.
Results 260 Infants were included. A significantly higher proportion of patients were started on levothyroxine (LT4) in no ANS group and partial ANS group compared to complete ANS group. Logistic regression analysis revealed that infants in no ANS group are more likely to have TSH > 6 mu IU ml(-1) and started on LT4 compared to complete ANS group.
Conclusion Infants in no ANS group are more likely to have thyroid dysfunction compared to complete ANS group.
Details
- Title: Subtitle
- Antenatal steroids and thyroid hormone function in preterm infants
- Creators
- Dinushan C. Kaluarachchi - University of Wisconsin–MadisonQianqian Zhao - University of Wisconsin–MadisonTarah T. Colaizy - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of perinatology, Vol.38(11), pp.1466-1470
- Publisher
- Springer Nature
- DOI
- 10.1038/s41372-018-0225-5
- PMID
- 30206348
- ISSN
- 0743-8346
- eISSN
- 1476-5543
- Number of pages
- 5
- Language
- English
- Date published
- 11/01/2018
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9984353828802771
Metrics
11 Record Views