Anterior Segment Dysgenesis and Early-Onset Glaucoma in nee Mice with Mutation of Sh3pxd2b

Mao Mao; Adam Hedberg-Buenz; Demelza Koehn; Simon W. M John; Michael G Anderson

doi:10.1167/iovs.10-5993

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Anterior Segment Dysgenesis and Early-Onset Glaucoma in nee Mice with Mutation of Sh3pxd2b

Journal article

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Anterior Segment Dysgenesis and Early-Onset Glaucoma in nee Mice with Mutation of Sh3pxd2b

Mao Mao, Adam Hedberg-Buenz, Demelza Koehn, Simon W. M John and Michael G Anderson

Investigative ophthalmology & visual science, Vol.52(5), pp.2679-2688

04/2011

DOI: 10.1167/iovs.10-5993

PMCID: PMC3088558

PMID: 21282566

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Abstract

This study demonstrates an early-onset form of glaucoma in mice with the nee mutation of the Sh3pxd2b gene. This finding implicates podosomes as having a role in glaucoma and creates a new animal model of glaucoma with broad applicability.

Details

Title: Subtitle: Anterior Segment Dysgenesis and Early-Onset Glaucoma in nee Mice with Mutation of Sh3pxd2b
Creators: Mao Mao - From the Departments of
Adam Hedberg-Buenz - From the Departments of
Demelza Koehn - From the Departments of
Simon W. M John - the
Michael G Anderson - From the Departments of
Resource Type: Journal article
Publication Details: Investigative ophthalmology & visual science, Vol.52(5), pp.2679-2688
DOI: 10.1167/iovs.10-5993
PMID: 21282566
PMCID: PMC3088558
NLM abbreviation: Invest Ophthalmol Vis Sci
ISSN: 0146-0404
eISSN: 1552-5783
Publisher: Association for Research in Vision and Ophthalmology, Inc
Language: English
Date published: 04/2011
Academic Unit: Molecular Physiology and Biophysics; Ophthalmology and Visual Sciences
Record Identifier: 9984025327602771

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