Journal article
Antibacterial diterpenoids from Jatropha podagrica Hook
Phytochemistry (Oxford), Vol.68(19), pp.2420-2425
2007
DOI: 10.1016/j.phytochem.2007.05.021
PMID: 17604062
Abstract
Two macrocyclic diterpenoids (
1 and
2) possessing lathyrane and jatrophane skeletons, respectively were isolated from the root extracts of
Jatropha podagrica by a combination of chromatographic techniques including reversed-phase HPLC. The compounds exhibited antibacterial activity against some gram-positive bacteria.
Japodagrin (
1) and japodagrone (
2), two macrocylic diterpenoids possessing lathyrane and jatrophane skeletons, respectively, have been isolated from the root of
Jatropha podagrica Hook. Four other diterpenoids (
3–
6) were also isolated from this plant. The structures of these compounds were elucidated on the basis of NMR and HRMS analysis, and by spectral comparisons. The compounds displayed antibacterial activity against some gram-positive bacteria.
Details
- Title: Subtitle
- Antibacterial diterpenoids from Jatropha podagrica Hook
- Creators
- Olapeju O Aiyelaagbe - Department of Chemistry, University of Ibadan, Ibadan, NigeriaKayode Adesogan - Department of Chemistry, University of Ibadan, Ibadan, NigeriaOlusegun Ekundayo - Department of Chemistry, University of Ibadan, Ibadan, NigeriaJames B Gloer - Department of Chemistry, University of Iowa, Iowa City, IA 52242, USA
- Resource Type
- Journal article
- Publication Details
- Phytochemistry (Oxford), Vol.68(19), pp.2420-2425
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.phytochem.2007.05.021
- PMID
- 17604062
- ISSN
- 0031-9422
- eISSN
- 1873-3700
- Language
- English
- Date published
- 2007
- Academic Unit
- Chemistry
- Record Identifier
- 9984216669502771
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