Journal article
Antibodies to GM1 and GD1b in patients with motor neuron disease without plasma cell dyscrasia
Annals of neurology, Vol.25(5), pp.511-513
05/1989
DOI: 10.1002/ana.410250517
PMID: 2505666
Abstract
Fiftynine percent of 49 patients with motor neuron disease and 25% of 91 control subjects had IgM antibodies to ganglioside GM1 but usually not to GD1b at titers less than 1:80. This suggests that antibodies to GM1 may be part of the normal human antibody repertoire. However, given the higher incidence of antibodies to GM1 in patients with motor neuron disease, there may be specific epitopes important in antiganglioside antibodies associated with motor neuron disease.
Details
- Title: Subtitle
- Antibodies to GM1 and GD1b in patients with motor neuron disease without plasma cell dyscrasia
- Creators
- Michael E ShyVance A EvansFred D LublinRobert L KnoblerTerry Heiman‐PattersonAlbert J TahmoushGareth ParryPaul SchickTheodora G Deryk
- Resource Type
- Journal article
- Publication Details
- Annals of neurology, Vol.25(5), pp.511-513
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company; Hoboken
- DOI
- 10.1002/ana.410250517
- PMID
- 2505666
- ISSN
- 0364-5134
- eISSN
- 1531-8249
- Number of pages
- 3
- Language
- English
- Date published
- 05/1989
- Academic Unit
- Neurology; Molecular Physiology and Biophysics; Stead Family Department of Pediatrics; Iowa Neuroscience Institute
- Record Identifier
- 9984020748702771
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