Journal article
Anticipated impact of recent ethanol lock shortage and price increase on practice among pediatric intestinal rehabilitation programs across the United States
JPEN. Journal of parenteral and enteral nutrition, Vol.46(2), pp.319-323
02/01/2022
DOI: 10.1002/jpen.2128
PMID: 33914379
Abstract
Background Ethanol lock use has been associated with significantly lower rates of central line-associated bloodstream infection (CLABSI) in children with intestinal failure. Concerns have been raised among intestinal rehabilitation program providers regarding the impact of recent changes in cost and availability of ethanol locks in the US.
Methods We conducted a survey among the members of the North American Society For Pediatric Gastroenterology, Hepatology & Nutrition Intestinal Rehabilitation Special Interest Group (NASPGHAN IR-SIG) regarding practice changes among providers to tackle this issue and the anticipated effect on CLABSI rates.
Results The results show that the vast majority of US participants use ethanol locks in their population with intestinal failure, with most anticipating or already experiencing reduction in access to ethanol locks. Most worrisome is that more than half of participating programs expect an increase in CLABSI rates in this vulnerable patient population as a consequence of limited access to ethanol locks.
Conclusion Further multicenter prospective studies to assess the efficacy of alternative locking agents, besides ethanol, are needed in order to have readily available and affordable options for CLABSI prevention in the future.
Details
- Title: Subtitle
- Anticipated impact of recent ethanol lock shortage and price increase on practice among pediatric intestinal rehabilitation programs across the United States
- Creators
- Saurabh Talathi - University of Oklahoma Health Sciences CenterEthan Mezoff - Nationwide Children's HospitalDavid Galloway - University of Alabama at BirminghamRiad Rahhal - University of Iowa
- Resource Type
- Journal article
- Publication Details
- JPEN. Journal of parenteral and enteral nutrition, Vol.46(2), pp.319-323
- Publisher
- Wiley
- DOI
- 10.1002/jpen.2128
- PMID
- 33914379
- ISSN
- 0148-6071
- eISSN
- 1941-2444
- Number of pages
- 5
- Grant note
- NASPGHAN Intestinal Rehabilitation Special Interest Group
- Language
- English
- Date published
- 02/01/2022
- Academic Unit
- Stead Family Department of Pediatrics; Gastroenterology, Hepatology, Pancreatology, and Nutrition
- Record Identifier
- 9984354150902771
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