Journal article
Antifungal and Antibacterial Metabolites from a Sclerotium-Colonizing Isolate of Mortierella vinacea
Journal of natural products (Washington, D.C.), Vol.62(2), pp.386-388
02/01/1999
DOI: 10.1021/np980411h
PMID: 10075797
Abstract
The known compound methyl 2,4-dihydroxy-3,5,6-trimethylbenzoate (1) and three new related metabolites, which we have named mortivinacins A (2), B (3), and C (4), were identified as metabolites of the fungus Mortierella vinacea. Nicotinic acid (5) was also encountered. This isolate of M. vinacea was obtained from an Aspergillus flavus sclerotium during field studies of sclerotium longevity in soil. Compounds 1-5 were isolated by chromatographic fractionation of organic extracts from M. vinacea solid-substrate fermentation cultures, and the structures were assigned by analysis of NMR and MS data. Compounds 1, 2, and 5 were responsible for the antibacterial and antifungal activities of the extract.
Details
- Title: Subtitle
- Antifungal and Antibacterial Metabolites from a Sclerotium-Colonizing Isolate of Mortierella vinacea
- Creators
- Ashish G Soman - Department of Chemistry, University of Iowa, Iowa City, Iowa, 52242, and Bioactive Agents Research Unit, Agricultural Research Service, National Center for Agricultural Utilization Research, USDA, Peoria, Illinois, 61604James B Gloer - Department of Chemistry, University of Iowa, Iowa City, Iowa, 52242, and Bioactive Agents Research Unit, Agricultural Research Service, National Center for Agricultural Utilization Research, USDA, Peoria, Illinois, 61604Donald T Wicklow - Department of Chemistry, University of Iowa, Iowa City, Iowa, 52242, and Bioactive Agents Research Unit, Agricultural Research Service, National Center for Agricultural Utilization Research, USDA, Peoria, Illinois, 61604
- Resource Type
- Journal article
- Publication Details
- Journal of natural products (Washington, D.C.), Vol.62(2), pp.386-388
- DOI
- 10.1021/np980411h
- PMID
- 10075797
- ISSN
- 0163-3864
- eISSN
- 1520-6025
- Language
- English
- Date published
- 02/01/1999
- Academic Unit
- Chemistry
- Record Identifier
- 9984216691102771
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