Journal article
Antimalarial lichenoid tissue reactions in patients with pre-existing lupus erythematosus
Lupus, Vol.13(6), pp.473-477
06/2004
DOI: 10.1191/0961203304lu1056cr
PMID: 15303576
Abstract
Recently a number of cases of drug induction or exacerbation of lupus erythematosus (LE) specific skin disease have been described in the literature. Many of the responsible medications are also known for their ability to induce a lichenoid tissue reaction. Aminoquinoline antimalarials are currently the first line of therapy in cutaneous LE specific skin disease. Lichenoid tissue reactions are among the most common cutaneous side effects of aminoquinolone antimalarials. We report three cases of aminoquinolone antimalarial induced or exacerbated LE specific skin disease. We also review the pathophysiology of LE specific skin disease and propose a mechanism by which induction of the lichenoid tissue reaction may result in Koebnerization of LE specific skin lesions.
Details
- Title: Subtitle
- Antimalarial lichenoid tissue reactions in patients with pre-existing lupus erythematosus
- Creators
- P Geraminejad - Department of Dermatology, University of Iowa, Iowa city, IA, USAM S Stone - Department of Dermatology, University of Iowa, Iowa city, IA, USAR D Sontheimer - Department of Dermatology, University of Iowa, Iowa city, IA, USA
- Resource Type
- Journal article
- Publication Details
- Lupus, Vol.13(6), pp.473-477
- Publisher
- Sage Publications; Thousand Oaks, CA
- DOI
- 10.1191/0961203304lu1056cr
- PMID
- 15303576
- ISSN
- 0961-2033
- eISSN
- 1477-0962
- Language
- English
- Date published
- 06/2004
- Academic Unit
- Dermatology; Pathology
- Record Identifier
- 9984025577602771
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