Journal article
Antithrombotic Therapy for VTE Disease: Compendium and Review of CHEST Guidelines 2012-2021
Chest, Vol.166(2), pp.388-404
08/2024
DOI: 10.1016/j.chest.2024.03.003
PMID: 38458430
Abstract
The CHEST Antithrombotic Therapy for Venous Thromboembolism Disease evidencebased guidelines are now updated in a more frequent, focused manner. Guidance statements from the most recent full guideline and two subsequent updates have not been gathered into a single source. METHODS An international panel of experts with experience in prior Antithrombotic Therapy guideline development reviewed the 2012 CHEST Antithrombotic Therapy guideline and its two subsequent updates. All guideline statements, and their associated Patient, Intervention, Comparator, Outcome questions were assembled. A modified Delphi process was used to select statements considered relevant to current clinical care. The panel further endorsed minor phrasing changes to match the standard language for guidance statements using the modified GRADE format endorsed by the CHEST Guidelines Oversight Committee. The panel appended comments following statements as deemed relevant, including suggesting which statements be updated in future guidelines due to interval evidence. RESULTS We include 58 guidance statements from prior versions of the antithrombotic therapy guidelines, with updated phrasing as needed to adhere to contemporary nomenclature. Statements are classified as strong or weak recommendations based on high, moderate, and low-certainty evidence, using GRADE methodology. The panel suggests that 5 statements are no longer relevant to current practice. CONCLUSION As CHEST continues to update guidance statements relevant to antithrombotic therapy for VTE disease, this manuscript serves as a unified collection of currently relevant statements from the preceding three guidelines. Suggestions are made to update specific statements in future publications.
Details
- Title: Subtitle
- Antithrombotic Therapy for VTE Disease: Compendium and Review of CHEST Guidelines 2012-2021
- Creators
- Scott M Stevens - Intermountain HealthcareScott C Woller - Intermountain HealthcareLisa Baumann Kreuziger - Medical College of WisconsinKevin Doerschug - University of IowaGeert-Jan Geersing - University Medical Center UtrechtFrederikus A Klok - Leiden University Medical CenterChristopher S King - Inova Fairfax HospitalSusan Murin - University of California, DavisJanine R E Vintch - The Lundquist InstitutePhilip S Wells - University of OttawaSuman Wasan - University of North Carolina at Chapel HillLisa K Moores - Uniformed Services University of the Health Sciences
- Resource Type
- Journal article
- Publication Details
- Chest, Vol.166(2), pp.388-404
- DOI
- 10.1016/j.chest.2024.03.003
- PMID
- 38458430
- NLM abbreviation
- Chest
- ISSN
- 0012-3692
- eISSN
- 1931-3543
- Publisher
- ELSEVIER
- Grant note
Funding/Support The authors have reported to CHEST that no funding was received for this study. However, CHEST at the discretion of the CHEST Guidelines Oversight Committee provided material support and endorsement of the guidelines summarized herein. Financial/Nonfinancial Disclosures The authors have reported to CHEST the following: L. B. K. reports receiving research funding from CSL Behring and Takeda to her institution for unrelated research. None declared S. M. S., S. C. W., K. D., G.-J. G., F. A. K., C. S. K., S. M., J. R. E. V., P. S. W., S. W., and L. K. M.
- Language
- English
- Electronic publication date
- 03/06/2024
- Date published
- 08/2024
- Academic Unit
- Pulmonary, Critical Care, and Occupational Medicine; Internal Medicine
- Record Identifier
- 9984568047802771
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