Journal article
Antiviral drugs for treatment of patients infected with pandemic (H1N1) 2009 virus
Emerging Infectious Diseases, Vol.15(10), pp.1851-1852
2009
DOI: 10.3201/eid1511.090720
PMCID: PMC2857246
PMID: 19891884
Abstract
To the Editor: The emergence of influenza A pandemic (H1N1) 2009 virus in North America and associated illness and death suggest that humanity faces a dangerous threat. Viruses isolated from a sample of patients with confirmed cases in early phases of the outbreak demonstrated resistance to amantadine and rimantadine. At present, circulating viruses appear to be largely susceptible to the neuraminidase inhibitors oseltamivir and zanamivir, although oseltamivir resistance has been observed in recent cases in Europe, Asia, and North America (1). More recently, pandemic (H1N1) 2009 virus resistance to oseltamivir emerged during treatment of 2 immunosuppressed patients in the United States. Such cases demonstrate that oseltamivir resistance can emerge in infected persons treated with oseltamivir. To date, all isolates tested have been susceptible to zanamivir.
Details
- Title: Subtitle
- Antiviral drugs for treatment of patients infected with pandemic (H1N1) 2009 virus
- Creators
- David M HartleyNoele P NelsonEli N Perencevich
- Resource Type
- Journal article
- Publication Details
- Emerging Infectious Diseases, Vol.15(10), pp.1851-1852
- DOI
- 10.3201/eid1511.090720
- PMID
- 19891884
- PMCID
- PMC2857246
- NLM abbreviation
- Emerg Infect Dis
- ISSN
- 1080-6040
- eISSN
- 1080-6059
- Language
- English
- Date published
- 2009
- Academic Unit
- Epidemiology; Internal Medicine
- Record Identifier
- 9983779493002771
Metrics
26 Record Views