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Anxiety and cerebral cortical metabolism in normal persons
Journal article   Peer reviewed

Anxiety and cerebral cortical metabolism in normal persons

Bruno Giordani, Michael J Boivin, Stanley Berent, Annette T Betley, Robert A Koeppe, Jill M Rothley, Jack G Modell, Richard D Hichwa and David E Kuhl
Psychiatry research. Neuroimaging, Vol.35(1), pp.49-60
1990
DOI: 10.1016/0925-4927(90)90008-T
url
https://hdl.handle.net/2027.42/28630View
Open Access

Abstract

The State-Trait Anxiety Inventory (STAI) was administered to 43 normal volunteers immediately before and after a positron emission tomography (PET) procedure with [ 18F]-2-fluoro-2-deoxy-D-glucose ( 18F-FDG). High traitanxious individuals had significantly higher state (situational) anxiety associated with the PET scan procedure than did low trait-anxious persons. State anxiety decreased significantly for all respondents following the PET scan procedure. No significant relationships between global or regional cortical metabolic rates and state anxiety were observed. The direct cortical metabolic effects of heightened anxiety in the scan setting, should they exist, are likely obscured in the normal variance of the 18F-FDG method.
anxiety cerebral metabolic rate cortical lateralization frontal lobe Positron emission tomography State-Trait Anxiety Inventory

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