Journal article
Apathy Is Not Depression
The journal of neuropsychiatry and clinical neurosciences, Vol.10(3), pp.314-319
08/1998
DOI: 10.1176/jnp.10.3.314
PMID: 9706539
Abstract
If depression is associated with apathy, then they should be expressed together in different dementia syndromes and should co-occur at varying levels of disease severity. The authors performed a cross-sectional comparison of neuropsychiatric symptoms in 30 Alzheimer's disease, 28 frontotemporal dementia, 40 Parkinson's disease, 34 Huntington's disease, and 22 progressive supranuclear palsy patients, using a standardized rating scale (the Neuropsychiatric Inventory). Apathy did not correlate with depression in the combined sample; apathy (r= -0.40, P<0.0001), but not depression, correlated with lower cognitive function as measured by the Mini-Mental State Examination. The relationship of apathy to depression also varied across diagnostic groups. Apathy is a specific neuropsychiatric syndrome that is distinct from depression. Distinguishing these two syndromes has therapeutic implications.
Details
- Title: Subtitle
- Apathy Is Not Depression
- Creators
- Morgan L LevyJeffrey L CummingsLynn A FairbanksDonna MastermanBruce L MillerAnne H CraigJane S PaulsenIrene Litvan
- Resource Type
- Journal article
- Publication Details
- The journal of neuropsychiatry and clinical neurosciences, Vol.10(3), pp.314-319
- Publisher
- American Psychiatric Publishing
- DOI
- 10.1176/jnp.10.3.314
- PMID
- 9706539
- ISSN
- 0895-0172
- eISSN
- 1545-7222
- Language
- English
- Date published
- 08/1998
- Academic Unit
- Psychiatry; Psychological and Brain Sciences
- Record Identifier
- 9984083859502771
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