Journal article
Apparent central nervous system depression in infants after the use of topical brimonidine
American journal of ophthalmology, Vol.128(2), pp.255-256
08/1999
DOI: 10.1016/S0002-9394(99)00083-5
PMID: 10458196
Abstract
To report two cases in which topical brimonidine resulted in apparent central nervous system depression and unresponsiveness in an infant. Review of two patients. An 11-day-old infant became lethargic and apneic after a single drop of brimonidine. These symptoms were reproduced after a second administration of brimonidine. A 5-month-old infant became lethargic and poorly responsive after receiving 1 drop of brimonidine in each eye. The first patient required admission to the hospital for medical stabilization. He recovered without sequelae. The second patient recovered spontaneously approximately 2.5 hours after administration of brimonidine. Topical brimonidine may be associated with central nervous system depression in infants. The use of brimonidine is not recommended in these patients until further data are available.
Details
- Title: Subtitle
- Apparent central nervous system depression in infants after the use of topical brimonidine
- Creators
- J O Carlsen - John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City 84132, USAN A ZabriskieY H KwonM E BarbeW E Scott
- Resource Type
- Journal article
- Publication Details
- American journal of ophthalmology, Vol.128(2), pp.255-256
- Publisher
- United States
- DOI
- 10.1016/S0002-9394(99)00083-5
- PMID
- 10458196
- ISSN
- 0002-9394
- eISSN
- 1879-1891
- Language
- English
- Date published
- 08/1999
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9983980291402771
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