Logo image
Apparent diffusion coefficient of normal adrenal glands
Journal article   Open access   Peer reviewed

Apparent diffusion coefficient of normal adrenal glands

Sara Reis Teixeira, Paula Condé Lamparelli Elias, Andrea Farias de Melo Leite, Tatiane Mendes Gonçalves de Oliveira, Valdair Francisco Muglia, Jorge Elias Junior and Instituto de Medicina Integral Professor Fernando Figueira de Pernambuco, Brazil
Radiologia brasileira, Vol.49(6), pp.363-368
11/01/2016
DOI: 10.1590/0100-3984.2015.0045
PMID: 28057963
url
https://doi.org/10.1590/0100-3984.2015.0045View
Published (Version of record) Open Access

Abstract

Objective: To assess the feasibility and reliability of apparent diffusion coefficient (ADC) measurements of normal adrenal glands. Materials and methods: This was a retrospective study involving 32 healthy subjects, divided into two groups: prepubertal (PreP, n = 12), aged from 2 months to 12.5 years (4 males; 8 females); and postpubertal (PostP, n = 20), aged from 11.9 to 61 years (5 males; 15 females). Diffusion-weighted magnetic resonance imaging (DW-MRI) sequences were acquired at a 1.5 T scanner using b values of 0, 20, 500, and 1000 s/mm2. Two radiologists evaluated the images. ADC values were measured pixel-by-pixel on DW-MRI scans, and automatic co-registration with the ADC map was obtained. Results: Mean ADC values for the right adrenal glands were 1.44 × 10-3 mm2/s for the PreP group and 1.23 × 10-3 mm2/s for the PostP group, whereas they were 1.58 × 10-3 mm2/s and 1.32 × 10-3 mm2/s, respectively, for the left glands. ADC values were higher in the PreP group than in the PostP group (p < 0.05). Agreement between readers was almost perfect (intraclass correlation coefficient, 0.84-0.94; p < 0.05). Conclusion: Our results demonstrate the feasibility and reliability of performing DW-MRI measurements of normal adrenal glands. They could also support the feasibility of ADC measurements of small structures.
Magnetic Resonance Imaging Adrenal glands Diffusion magnetic resonance imaging

Details

Metrics

1 Record Views
Logo image