Journal article
Apparent diffusion coefficient of normal adrenal glands
Radiologia brasileira, Vol.49(6), pp.363-368
11/01/2016
DOI: 10.1590/0100-3984.2015.0045
PMID: 28057963
Abstract
Objective: To assess the feasibility and reliability of apparent diffusion coefficient (ADC) measurements of normal adrenal glands.
Materials and methods: This was a retrospective study involving 32 healthy subjects, divided into two groups: prepubertal (PreP, n = 12), aged from 2 months to 12.5 years (4 males; 8 females); and postpubertal (PostP, n = 20), aged from 11.9 to 61 years (5 males; 15 females). Diffusion-weighted magnetic resonance imaging (DW-MRI) sequences were acquired at a 1.5 T scanner using b values of 0, 20, 500, and 1000 s/mm2. Two radiologists evaluated the images. ADC values were measured pixel-by-pixel on DW-MRI scans, and automatic co-registration with the ADC map was obtained.
Results: Mean ADC values for the right adrenal glands were 1.44 × 10-3 mm2/s for the PreP group and 1.23 × 10-3 mm2/s for the PostP group, whereas they were 1.58 × 10-3 mm2/s and 1.32 × 10-3 mm2/s, respectively, for the left glands. ADC values were higher in the PreP group than in the PostP group (p < 0.05). Agreement between readers was almost perfect (intraclass correlation coefficient, 0.84-0.94; p < 0.05).
Conclusion: Our results demonstrate the feasibility and reliability of performing DW-MRI measurements of normal adrenal glands. They could also support the feasibility of ADC measurements of small structures.
Details
- Title: Subtitle
- Apparent diffusion coefficient of normal adrenal glands
- Creators
- Sara Reis Teixeira - Universidade de Ribeirão PretoPaula Condé Lamparelli Elias - Clinics Hospital of Ribeirão PretoAndrea Farias de Melo Leite - Instituto de Medicina Integral Professor Fernando FigueiraTatiane Mendes Gonçalves de Oliveira - Clinics Hospital of Ribeirão PretoValdair Francisco Muglia - Universidade de Ribeirão PretoJorge Elias Junior - Radiology Division, Department of Internal Medicine, Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP, BrazilInstituto de Medicina Integral Professor Fernando Figueira de Pernambuco, Brazil
- Resource Type
- Journal article
- Publication Details
- Radiologia brasileira, Vol.49(6), pp.363-368
- DOI
- 10.1590/0100-3984.2015.0045
- PMID
- 28057963
- ISSN
- 0100-3984
- eISSN
- 0100-3984
- Number of pages
- 6
- Language
- English
- Date published
- 11/01/2016
- Academic Unit
- Radiology
- Record Identifier
- 9985214170602771
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