Journal article
Application of an alternative approach for using the SOS chromotest to screen complex indeterminate mixtures
Zentralblatt für Mikrobiologie, Vol.145(3), pp.177-182
1990
DOI: 10.1016/S0232-4393(11)80132-0
PMID: 2196748
Abstract
We report on the application of an alternative approach to screen two complex indeterminate mixtures for genotoxic activity with the SOS chromotest, a simple quantitative colorimetric short-term bacterial genotoxicity assay. Considering the mixtures as a complex matrix, we evaluated the shape of the dose response curve of the direct acting reference genotoxin 4-nitroquinoline-1-oxide (4-NQO) with and without the matrix and found for one mixture a previously unrecognized genotoxic potential.
Details
- Title: Subtitle
- Application of an alternative approach for using the SOS chromotest to screen complex indeterminate mixtures
- Creators
- S JANZ - Karl Marx univ., fac. medicine, inst. clinical immunology, Leipzig 7010, German Democratic RepublicF RAABE - Karl Marx univ., fac. medicine, inst. clinical immunology, Leipzig 7010, German Democratic RepublicG WOLFF - Karl Marx univ., fac. medicine, inst. clinical immunology, Leipzig 7010, German Democratic Republic
- Resource Type
- Journal article
- Publication Details
- Zentralblatt für Mikrobiologie, Vol.145(3), pp.177-182
- Publisher
- Fischer
- DOI
- 10.1016/S0232-4393(11)80132-0
- PMID
- 2196748
- ISSN
- 0232-4393
- Language
- English
- Date published
- 1990
- Academic Unit
- Pathology
- Record Identifier
- 9984083204402771
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