Application of benzyl protecting groups in the synthesis of prenylated aromatic compounds

Sina I Odejinmi; David F Wiemer

doi:10.1016/j.tetlet.2005.03.187

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Application of benzyl protecting groups in the synthesis of prenylated aromatic compounds

Journal article

Peer reviewed

Application of benzyl protecting groups in the synthesis of prenylated aromatic compounds

Sina I Odejinmi and David F Wiemer

Tetrahedron letters, Vol.46(22), pp.3871-3874

2005

DOI: 10.1016/j.tetlet.2005.03.187

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Abstract

[Display omitted] Benzyl ethers have proven to be useful protecting groups for synthesis of phenols bearing isoprenoid chains because the benzyl groups can tolerate the conditions of halogen–metal exchange used to introduce the side chains yet are cleaved in good yields upon treatment with sodium s-butanol.

Protecting group

Piperoic acid

Benzyl ether

Montadial

Details

Title: Subtitle: Application of benzyl protecting groups in the synthesis of prenylated aromatic compounds
Creators: Sina I Odejinmi
David F Wiemer
Resource Type: Journal article
Publication Details: Tetrahedron letters, Vol.46(22), pp.3871-3874
Publisher: Elsevier Ltd
DOI: 10.1016/j.tetlet.2005.03.187
ISSN: 0040-4039
eISSN: 1873-3581
Language: English
Date published: 2005
Academic Unit: Chemistry; Neuroscience and Pharmacology
Record Identifier: 9983985938902771

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