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Applications of hydrogen-bond-acceptor templates to direct 'in-phase' reactivity of a diene diacid in the solid state
Journal article   Open access   Peer reviewed

Applications of hydrogen-bond-acceptor templates to direct 'in-phase' reactivity of a diene diacid in the solid state

Manza B J Atkinson, Anatoliy N Sokolov, Dejan-Krešimir Bučar, S V Santhana Mariappan, Martin T Mwangi, Michael C Tiedman and Leonard R MacGillivray
Photochemical & photobiological sciences, Vol.10(9), pp.1384-1386
09/2011
DOI: 10.1039/c1pp05077j
PMID: 21479316
url
https://doi.org/10.1039/c1pp05077jView
Published (Version of record) Open Access

Abstract

The hydrogen-bond-acceptor (HBA) templates 2,3-bis(4-methylenethiopyridyl)naphthalene (2,3-nap) and 1,8-bis(4-pyridyl)naphthalene (1,8-dpn) are used to assemble (E,E)-2,5-dimethylmuconic acid (dmma) in the solid state for an intermolecular [2 + 2] photocycloaddition. Co-crystallisation of 2,3-nap with dmma affords an 1D hydrogen-bonded polymer that is photostable while 1,8-nap affords a 0D hydrogen-bonded assembly that is photoactive. The diene stacks in-phase and reacts to give a syn monocyclobutane in up to 55% yield.

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